ID   COQ4_PLACH              Reviewed;         354 AA.
AC   Q4XQW7;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111};
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog {ECO:0000255|HAMAP-Rule:MF_03111};
GN   ORFNames=PC000176.04.0;
OS   Plasmodium chabaudi.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5825;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AS;
RX   PubMed=15637271; DOI=10.1126/science.1103717;
RA   Hall N., Karras M., Raine J.D., Carlton J.M., Kooij T.W.A., Berriman M.,
RA   Florens L., Janssen C.S., Pain A., Christophides G.K., James K.,
RA   Rutherford K., Harris B., Harris D., Churcher C.M., Quail M.A., Ormond D.,
RA   Doggett J., Trueman H.E., Mendoza J., Bidwell S.L., Rajandream M.A.,
RA   Carucci D.J., Yates J.R. III, Kafatos F.C., Janse C.J., Barrell B.G.,
RA   Turner C.M.R., Waters A.P., Sinden R.S.;
RT   "A comprehensive survey of the Plasmodium life cycle by genomic,
RT   transcriptomic, and proteomic analyses.";
RL   Science 307:82-86(2005).
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC       role in organizing a multi-subunit COQ enzyme complex required for
CC       coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC       polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
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DR   EMBL; CAAJ01003867; CAH80695.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4XQW7; -.
DR   SMR; Q4XQW7; -.
DR   VEuPathDB; PlasmoDB:PCHAS_0908900; -.
DR   eggNOG; KOG3244; Eukaryota.
DR   InParanoid; Q4XQW7; -.
DR   UniPathway; UPA00232; -.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03111; Coq4; 1.
DR   InterPro; IPR007715; Coq4.
DR   InterPro; IPR027540; Coq4_euk.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..354
FT                   /note="Ubiquinone biosynthesis protein COQ4 homolog,
FT                   mitochondrial"
FT                   /id="PRO_0000388078"
SQ   SEQUENCE   354 AA;  42335 MW;  775CFCEBD15B0797 CRC64;
     MNNFAKIFQS NWIDLNKLGK LEIFLKTISG IYKAPNRTHL LAHAADISSF YAVKNIYEYM
     KNDDEGKVIL KNKPLLIRQD IQFNELKKLP KNTLGYKYME FLEAYKLHAH DREAAHFFDD
     INYSYILTRY RQIHDIGHVV YNLNISIESE AALKMIELIH TKLPITLLAI LVAPFMTPLY
     RFQYIFKDKI PPNFLNPNFD YTYKDDYNYI DELSLKQYVY NLTEYFHIDK IDNNIFFQKL
     YKYYFDNLNN SNNIRGTIIY GYNNEDNNDI IFDDINNEYI FLKNPEKNYF LFKYKPRQTL
     LKQLYPWAYM AGMAATKPLH SIHIENWLKD IDLFRKTYNI IPLPDHLNLM SGIN