ID   COQ9_DICDI              Reviewed;         307 AA.
AC   Q86HS0; Q555A5;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable ubiquinone biosynthesis protein coq9, mitochondrial;
DE   Flags: Precursor;
GN   Name=coq9; ORFNames=DDB_G0274457;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Lipid-binding protein involved in the biosynthesis of
CC       coenzyme Q, also named ubiquinone, an essential lipid-soluble electron
CC       transporter for aerobic cellular respiration.
CC       {ECO:0000250|UniProtKB:O75208}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000250|UniProtKB:O75208}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q8K1Z0}.
CC   -!- SIMILARITY: Belongs to the COQ9 family. {ECO:0000305}.
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DR   EMBL; AAFI02000012; EAL70121.2; -; Genomic_DNA.
DR   RefSeq; XP_644168.2; XM_639076.2.
DR   AlphaFoldDB; Q86HS0; -.
DR   SMR; Q86HS0; -.
DR   STRING; 44689.DDB0266667; -.
DR   PaxDb; Q86HS0; -.
DR   EnsemblProtists; EAL70121; EAL70121; DDB_G0274457.
DR   GeneID; 8619597; -.
DR   KEGG; ddi:DDB_G0274457; -.
DR   dictyBase; DDB_G0274457; coq9.
DR   eggNOG; KOG2969; Eukaryota.
DR   HOGENOM; CLU_057411_0_0_1; -.
DR   InParanoid; Q86HS0; -.
DR   OMA; WFLAGDK; -.
DR   PhylomeDB; Q86HS0; -.
DR   UniPathway; UPA00232; -.
DR   PRO; PR:Q86HS0; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; ISS:dictyBase.
DR   GO; GO:0008289; F:lipid binding; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; ISS:dictyBase.
DR   InterPro; IPR013718; COQ9.
DR   InterPro; IPR012762; Ubiq_biosynth_COQ9.
DR   PANTHER; PTHR21427; PTHR21427; 1.
DR   Pfam; PF08511; COQ9; 1.
DR   TIGRFAMs; TIGR02396; diverge_rpsU; 1.
PE   3: Inferred from homology;
KW   Lipid-binding; Mitochondrion; Reference proteome; Transit peptide;
KW   Ubiquinone biosynthesis.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..307
FT                   /note="Probable ubiquinone biosynthesis protein coq9,
FT                   mitochondrial"
FT                   /id="PRO_0000339343"
FT   REGION          72..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         241..244
FT                   /ligand="1,2-diacylglycero-3-phosphoethanolamine"
FT                   /ligand_id="ChEBI:CHEBI:57613"
FT                   /evidence="ECO:0000250|UniProtKB:O75208"
SQ   SEQUENCE   307 AA;  35260 MW;  03A3535ED062446A CRC64;
     MISNILKKSN SLFLRSTLSS NKFTNVTILR NSLFLNNNNN DNNTNIKQTY NKINFFSTTV
     PNQNEKIELK QEQIKQEQQQ QPEQQPEQQT NKINNEIELK IKILENSLKY VNSYGWTSEA
     VSKACIEMGY PPITQGILGE DSAYELALYF VTKCNTDLMI KLSDAENSEQ QLLSGLSKKE
     KVKLALKLRL SMIKPFIGRW SEAMQLLANP KNIVNSSPSM LTLVDNIWYL VGDKSSDFDW
     YAKRGLLIAL YTSAELFMLS DTSVDHSNTW RFVDDRVDDL IKTIKFKNDI EETVGITLNT
     FLQKIKK