ID   COR2B_XENLA             Reviewed;         475 AA.
AC   Q6DJD8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Coronin-2B;
GN   Name=coro2b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye, and Tadpole;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the reorganization of neuronal actin
CC       structure. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat coronin family. {ECO:0000305}.
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DR   EMBL; BC075242; AAH75242.1; -; mRNA.
DR   EMBL; BC081222; AAH81222.1; -; mRNA.
DR   RefSeq; NP_001086406.1; NM_001092937.1.
DR   AlphaFoldDB; Q6DJD8; -.
DR   SMR; Q6DJD8; -.
DR   DNASU; 444835; -.
DR   GeneID; 444835; -.
DR   KEGG; xla:444835; -.
DR   CTD; 444835; -.
DR   Xenbase; XB-GENE-1014768; coro2b.L.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 444835; Expressed in camera-type eye and 17 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR027339; CORO2B.
DR   InterPro; IPR015505; Coronin.
DR   InterPro; IPR015048; DUF1899.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR10856; PTHR10856; 1.
DR   PANTHER; PTHR10856:SF17; PTHR10856:SF17; 1.
DR   Pfam; PF08953; DUF1899; 1.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM01166; DUF1899; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding; Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome;
KW   Repeat; WD repeat.
FT   CHAIN           1..475
FT                   /note="Coronin-2B"
FT                   /id="PRO_0000379778"
FT   REPEAT          80..120
FT                   /note="WD 1"
FT   REPEAT          130..172
FT                   /note="WD 2"
FT   REPEAT          174..212
FT                   /note="WD 3"
FT   REPEAT          215..258
FT                   /note="WD 4"
FT   REPEAT          260..303
FT                   /note="WD 5"
FT   COILED          431..470
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   475 AA;  54499 MW;  3655A0B26D6CBEE3 CRC64;
     MSWRPQYRCS KFRNVYGKVA SRENCYDCIP ITKNVHDNHF CAVNPKFLAI VTESAGGGSF
     FVIPLHQTGR IEPNYPKVCG HQGTVLDIKW NPFIENIIAS CSEDTSVRIW EIPDGGLKRN
     MTEAVLELYG HSRRVGLIEW HPTAINILFS AGYDYKILIW NLDVGEAVKM IDCHTDVILC
     MSFNTDGSLM ATTCKDKKLR VLEPRSGRVL QETTCKNHKV TRVVFFGDMK RLLTTGVSKW
     NTRQIALWDQ EDLSMPVTEE EIDGLSGLLF PFYDVDTHML YLAGKGDGNI RYYEITAEKP
     YLTYLMEFRS PAPQKGLGVM PKHGLDVSAC EIFRFYKLVT LKNQIEPISM IVPRRSENYQ
     EDIYPMTSGT EPALSPDEWL RGVNKGPVLM SLKEGYRKEN KAIYKAPVKE KKSLVVNGID
     LLENVPPRTE NELLRMFFKQ QEEIRRLKEQ LSQRDLLVRQ LELELKNLRN SPKDS