ID   CORC_BUCAI              Reviewed;         291 AA.
AC   P57518;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Magnesium and cobalt efflux protein CorC;
GN   Name=corC; OrderedLocusNames=BU443;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: Plays a role in the transport of magnesium and cobalt ions.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
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DR   EMBL; BA000003; BAB13141.1; -; Genomic_DNA.
DR   RefSeq; NP_240255.1; NC_002528.1.
DR   RefSeq; WP_009874397.1; NC_002528.1.
DR   AlphaFoldDB; P57518; -.
DR   SMR; P57518; -.
DR   STRING; 107806.10039107; -.
DR   EnsemblBacteria; BAB13141; BAB13141; BAB13141.
DR   KEGG; buc:BU443; -.
DR   PATRIC; fig|107806.10.peg.453; -.
DR   eggNOG; COG4535; Bacteria.
DR   HOGENOM; CLU_015237_3_0_6; -.
DR   OMA; QMISIKA; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cobalt; Magnesium; Reference proteome; Repeat; Transport.
FT   CHAIN           1..291
FT                   /note="Magnesium and cobalt efflux protein CorC"
FT                   /id="PRO_0000088342"
FT   DOMAIN          72..131
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          137..194
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   291 AA;  33465 MW;  6ADAE3B1A789CAB0 CRC64;
     MSDNHLQNSD KINRKGFFSI LLNQIFHDEP KNREELLVLI RDSEQNELID QDTCDMLEGV
     MHIAKKRIKE IMIPRTQMIT LKLHHNLNEC LDVIIESAHS RFPVMSNDNN YVEGFLIAKD
     LLPFMKQSAN IFCIKNILRP AVVVPESKHV DRMLKEFRSK RNHMAIVIDE FGAVSGLVTI
     EDILELIVGE IEDEYDDEET LNIRKIQKST FSIRALTEIK EFNETFNTNF SDEEVDTIGG
     LVMKEFGHLP SRGESINIDG YSFKISIADS RKVIQIHVTI PENKTPVLIE A