ID   CORC_SALTI              Reviewed;         292 AA.
AC   P0A2L4; O87575; Q9R874;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Magnesium and cobalt efflux protein CorC;
GN   Name=corC; OrderedLocusNames=STY0712, t2206;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Plays a role in the transport of magnesium and cobalt ions.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD05138.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69810.1; -; Genomic_DNA.
DR   RefSeq; NP_455236.1; NC_003198.1.
DR   RefSeq; WP_001278615.1; NZ_WSUR01000015.1.
DR   AlphaFoldDB; P0A2L4; -.
DR   SMR; P0A2L4; -.
DR   STRING; 220341.16501911; -.
DR   EnsemblBacteria; AAO69810; AAO69810; t2206.
DR   KEGG; stt:t2206; -.
DR   KEGG; sty:STY0712; -.
DR   PATRIC; fig|220341.7.peg.717; -.
DR   eggNOG; COG4535; Bacteria.
DR   HOGENOM; CLU_015237_3_0_6; -.
DR   OMA; ERRHMAL; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   SMART; SM00116; CBS; 2.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cobalt; Magnesium; Repeat; Transport.
FT   CHAIN           1..292
FT                   /note="Magnesium and cobalt efflux protein CorC"
FT                   /id="PRO_0000088350"
FT   DOMAIN          73..133
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          135..195
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   292 AA;  33299 MW;  54831AFCFACD2FBE CRC64;
     MSDDNSHSSD TVNSKKGFFS LLLSQLFHGE PKNRDELLAL IRDSGQNELI DEDTRDMLEG
     VMDIADQRVR DIMIPRSQMI TLKRNQTLDE CLDVIIESAH SRFPVISEDK DHIEGILMAK
     DLLPFMRSDA EAFSMDKVLR TAVVVPESKR VDRMLKEFRS QRYHMAIVID EFGGVSGLVT
     IEDILELIVG EIEDEYDEED DIDFRQLSRH TWTIRALASI EDFNDAFGTH FSDEEVDTIG
     GLVMQAFGHL PARGETIDID GYQFKVAMAD SRRIIQVHVR IPDDSPQPKL DE