ID   CORO6_RAT               Reviewed;         472 AA.
AC   Q920J3; Q4G087;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 2.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Coronin-6;
GN   Name=Coro6;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Tang H.B., Ip F.C.F., Cheung W.M.W., Ip N.Y.;
RT   "Cloning a novel rat coronin relative protein gene.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AF140359; AAK98517.1; -; mRNA.
DR   EMBL; BC098656; AAH98656.1; -; mRNA.
DR   RefSeq; NP_620815.2; NM_139115.2.
DR   RefSeq; XP_006246947.1; XM_006246885.3.
DR   AlphaFoldDB; Q920J3; -.
DR   SMR; Q920J3; -.
DR   BioGRID; 251471; 1.
DR   IntAct; Q920J3; 1.
DR   MINT; Q920J3; -.
DR   STRING; 10116.ENSRNOP00000019759; -.
DR   CarbonylDB; Q920J3; -.
DR   iPTMnet; Q920J3; -.
DR   PhosphoSitePlus; Q920J3; -.
DR   PaxDb; Q920J3; -.
DR   PRIDE; Q920J3; -.
DR   Ensembl; ENSRNOT00000019759; ENSRNOP00000019759; ENSRNOG00000014496.
DR   GeneID; 245982; -.
DR   KEGG; rno:245982; -.
DR   CTD; 84940; -.
DR   RGD; 708560; Coro6.
DR   eggNOG; KOG0303; Eukaryota.
DR   GeneTree; ENSGT00940000159328; -.
DR   HOGENOM; CLU_026859_0_1_1; -.
DR   InParanoid; Q920J3; -.
DR   OMA; FRHSTGH; -.
DR   OrthoDB; 552726at2759; -.
DR   PhylomeDB; Q920J3; -.
DR   TreeFam; TF314280; -.
DR   PRO; PR:Q920J3; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000014496; Expressed in heart and 20 other tissues.
DR   Genevisible; Q920J3; RN.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR027337; CORO6.
DR   InterPro; IPR015505; Coronin.
DR   InterPro; IPR015048; DUF1899.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR10856; PTHR10856; 1.
DR   PANTHER; PTHR10856:SF23; PTHR10856:SF23; 1.
DR   Pfam; PF08953; DUF1899; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM01166; DUF1899; 1.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..472
FT                   /note="Coronin-6"
FT                   /id="PRO_0000050933"
FT   REPEAT          79..119
FT                   /note="WD 1"
FT   REPEAT          129..169
FT                   /note="WD 2"
FT   REPEAT          173..212
FT                   /note="WD 3"
FT   REPEAT          216..259
FT                   /note="WD 4"
FT   REPEAT          264..304
FT                   /note="WD 5"
FT   REGION          409..434
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          430..469
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        419..434
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        77
FT                   /note="V -> I (in Ref. 1; AAK98517)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        100
FT                   /note="A -> P (in Ref. 1; AAK98517)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   472 AA;  52948 MW;  E0D0C22A97776F38 CRC64;
     MSRRVVRQSK FRHVFGQAAK ADQAYEDIRV SKVTWDSAFC AVNPKFLAII VEAGGGGAFI
     VLPLAKTGRV DKNYPLVTGH TGPVLDIDWC PHNDNVIASA SDDTTVMVWQ IPDYTPVRNI
     TEPVITLEGH SKRVGILSWH PTARNVLLSA GGDNVIIIWN VGTGEVLLSL DDIHPDVIHS
     VCWNSNGSLL ATTCKDKTLR IIDPRKSQVV AERFAAHEGM RPMRAVFTRL GHIFTTGFTR
     MSQRELGLWD PNNFEEPVAL QEMDTSNGVL LPFYDPDSSI VYLCGKGDSS IRYFEITDEP
     PFVHYLNTFS SKEPQRGMGF MPKRGLDVSK CEIARFYKLH ERKCEPIVMT VPRKSDLFQD
     DLYPDTPGPE PALEADEWLS GQDAEPVLIS LKEGYVPPKH REFRVTKRNI LDVRPPASPR
     RSQSASEAPL SQQHTLETLL EEMKALRERV QAQEERITAL ENMLCELVDG TD