位置:首页 > 蛋白库 > CORZ_CAMFO
CORZ_CAMFO
ID   CORZ_CAMFO              Reviewed;         101 AA.
AC   E2ARW3;
DT   14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 23.
DE   RecName: Full=Pro-corazonin {ECO:0000312|EMBL:EFN63812.1};
DE   Contains:
DE     RecName: Full=Corazonin {ECO:0000303|PubMed:25641051};
DE   Flags: Precursor;
GN   ORFNames=EAG_04993 {ECO:0000312|EMBL:EFN63812.1};
OS   Camponotus floridanus (Florida carpenter ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Formicinae; Camponotus.
OX   NCBI_TaxID=104421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 17-27, TISSUE SPECIFICITY, MASS SPECTROMETRY,
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND AMIDATION AT ASN-27.
RX   PubMed=25641051; DOI=10.1021/pr5011636;
RA   Schmitt F., Vanselow J.T., Schlosser A., Kahnt J., Roessler W., Wegener C.;
RT   "Neuropeptidomics of the carpenter ant Camponotus floridanus.";
RL   J. Proteome Res. 14:1504-1514(2015).
CC   -!- FUNCTION: Cardioactive peptide. Corazonin is probably involved in the
CC       physiological regulation of the heart beat.
CC       {ECO:0000250|UniProtKB:P11496}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25641051}.
CC   -!- TISSUE SPECIFICITY: Expressed in central brain and the retrocerebral
CC       complex but not in antennal lobes, optic lobes or in gnathal, thoracic
CC       and abdominal ganglia (at protein level).
CC       {ECO:0000269|PubMed:25641051}.
CC   -!- MASS SPECTROMETRY: [Corazonin]: Mass=1369.62; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:25641051};
CC   -!- SIMILARITY: Belongs to the corazonin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL442192; EFN63812.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2ARW3; -.
DR   STRING; 104421.E2ARW3; -.
DR   InParanoid; E2ARW3; -.
DR   OMA; LCQTFQY; -.
DR   Proteomes; UP000000311; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0071858; F:corazonin receptor binding; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IEA:InterPro.
DR   InterPro; IPR020190; Procorazonin.
DR   Pfam; PF17308; Corazonin; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Reference proteome;
KW   Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..101
FT                   /note="Pro-corazonin"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000434203"
FT   PEPTIDE         17..27
FT                   /note="Corazonin"
FT                   /evidence="ECO:0000269|PubMed:25641051"
FT                   /id="PRO_0000434204"
FT   PROPEP          31..101
FT                   /evidence="ECO:0000305|PubMed:25641051"
FT                   /id="PRO_0000434205"
FT   MOD_RES         27
FT                   /note="Asparagine amide"
FT                   /evidence="ECO:0000269|PubMed:25641051"
SQ   SEQUENCE   101 AA;  11587 MW;  27D57205E613C61F CRC64;
     MLVLFVLSLV VSCALCQTFQ YSRGWTNGKR SNFPAEISAL GYDRFTNGEL KRLKMLIYGS
     ADEQPLLIHC DFVDKLKKFA HTDNAEPDQL RREKAPNNDN Y
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024