ID   CORZ_PERAM              Reviewed;          11 AA.
AC   P11496;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 2.
DT   11-DEC-2019, entry version 52.
DE   RecName: Full=Corazonin;
OS   Periplaneta americana (American cockroach) (Blatta americana).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Blattidae;
OC   Blattinae; Periplaneta.
OX   NCBI_TaxID=6978;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT
RP   ASN-11.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=2753132; DOI=10.1016/0014-5793(89)80727-6;
RA   Veenstra J.A.;
RT   "Isolation and structure of corazonin, a cardioactive peptide from the
RT   American cockroach.";
RL   FEBS Lett. 250:231-234(1989).
CC   -!- FUNCTION: Cardioactive peptide. Corazonin is probably involved in the
CC       physiological regulation of the heart beat.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the corazonin family. {ECO:0000305}.
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DR   PIR; S05002; S05002.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..11
FT                   /note="Corazonin"
FT                   /id="PRO_0000043455"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:2753132"
FT   MOD_RES         11
FT                   /note="Asparagine amide"
FT                   /evidence="ECO:0000269|PubMed:2753132"
SQ   SEQUENCE   11 AA;  1387 MW;  C7CFF32D6415AB46 CRC64;
     QTFQYSRGWT N