ID   COTO_BACSU              Reviewed;         227 AA.
AC   O31622;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Spore coat protein O;
GN   Name=cotO; Synonyms=yjbX; OrderedLocusNames=BSU11730;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   FUNCTION.
RX   PubMed=16321932; DOI=10.1128/jb.187.24.8278-8290.2005;
RA   McPherson D.C., Kim H., Hahn M., Wang R., Grabowski P., Eichenberger P.,
RA   Driks A.;
RT   "Characterization of the Bacillus subtilis spore morphogenetic coat protein
RT   CotO.";
RL   J. Bacteriol. 187:8278-8290(2005).
CC   -!- FUNCTION: Has an important morphogenetic role. Involved in the assembly
CC       of at least five coat proteins, including CotB, CotG, CotS, CotSA and
CC       CotW. Required for appearance of a morphologically normal outer coat.
CC       To a large degree, CotO and CotH act at a late stage of coat assembly
CC       from within the outer coat to direct maturation of this structure.
CC       {ECO:0000269|PubMed:16321932}.
CC   -!- SUBCELLULAR LOCATION: Spore coat. Note=Localized in the outer spore
CC       coat.
CC   -!- MISCELLANEOUS: Largely but not entirely controlled by CotE.
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DR   EMBL; AL009126; CAB13030.1; -; Genomic_DNA.
DR   PIR; H69845; H69845.
DR   RefSeq; NP_389055.1; NC_000964.3.
DR   RefSeq; WP_010886484.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O31622; -.
DR   SMR; O31622; -.
DR   STRING; 224308.BSU11730; -.
DR   PaxDb; O31622; -.
DR   PRIDE; O31622; -.
DR   EnsemblBacteria; CAB13030; CAB13030; BSU_11730.
DR   GeneID; 939810; -.
DR   KEGG; bsu:BSU11730; -.
DR   eggNOG; ENOG503386N; Bacteria.
DR   OMA; LPHNMPR; -.
DR   BioCyc; BSUB:BSU11730-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR025439; Spore_coat_CotO.
DR   Pfam; PF14153; Spore_coat_CotO; 1.
PE   4: Predicted;
KW   Reference proteome; Sporulation.
FT   CHAIN           1..227
FT                   /note="Spore coat protein O"
FT                   /id="PRO_0000223374"
FT   REGION          1..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..67
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..157
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   227 AA;  25593 MW;  AE0DC234FE722F7B CRC64;
     MKMSNKKRNA DKKPLMYIVQ PDYAETTRSS MQEIVIKRKA DKPAPPKAEE KPAYHEKQQE
     EAVAQDVLQE DQKPAAEPVS QQTQEAREPE NIKSQEEQKA EPQAVEETVE HEPPKAEKKE
     EPALEARKPE KEPEAVHSAD KAEEKAPPAR KVKKPMSKMT IHEKIDFLTK LPHNMPRALC
     LIEANGRTYR GVIVGRRNDS VLLRTTGNGA PTELAIDDIT SLHPLGF