ID   COWN_RHORT              Reviewed;         101 AA.
AC   Q2RNI5;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=N(2)-fixation sustaining protein CowN;
DE   AltName: Full=CO weal-nitrogenase;
GN   Name=cowN; OrderedLocusNames=Rru_A3516;
OS   Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 /
OS   NCIMB 8255 / S1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=269796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1;
RX   PubMed=21886856; DOI=10.4056/sigs.1804360;
RA   Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K.,
RA   Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C.,
RA   Mavromatis K., Richardson P., Rohde M., Goeker M., Klenk H.P., Zhang Y.,
RA   Roberts G.P., Reslewic S., Schwartz D.C.;
RT   "Complete genome sequence of Rhodospirillum rubrum type strain (S1).";
RL   Stand. Genomic Sci. 4:293-302(2011).
RN   [2]
RP   FUNCTION IN N2-FIXATION, INDUCTION, DISRUPTION PHENOTYPE, AND GENE NAME.
RX   PubMed=21115659; DOI=10.1128/jb.00794-10;
RA   Kerby R.L., Roberts G.P.;
RT   "Sustaining N2-dependent growth in the presence of CO.";
RL   J. Bacteriol. 193:774-777(2011).
CC   -!- FUNCTION: Is required to sustain N(2)-dependent growth in the presence
CC       of low levels of carbon monoxide (CO). Probably acts by protecting the
CC       N(2) fixation ability of the nitrogenase complex, which is inactivated
CC       in the presence of CO. Is not required for CO-dependent growth.
CC       {ECO:0000269|PubMed:21115659}.
CC   -!- INDUCTION: Up-regulated by RcoM in the presence of CO. Its expression
CC       is enhanced in the presence of a poor nitrogen source, like glutamate,
CC       that allows nif derepression. {ECO:0000269|PubMed:21115659}.
CC   -!- DISRUPTION PHENOTYPE: Strains lacking this gene are not able to grow
CC       with N(2) as a nitrogen source in the presence of CO.
CC       {ECO:0000269|PubMed:21115659}.
CC   -!- SIMILARITY: Belongs to the CowN family. {ECO:0000305}.
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DR   EMBL; CP000230; ABC24310.1; -; Genomic_DNA.
DR   RefSeq; WP_011391263.1; NC_007643.1.
DR   RefSeq; YP_428597.1; NC_007643.1.
DR   AlphaFoldDB; Q2RNI5; -.
DR   STRING; 269796.Rru_A3516; -.
DR   EnsemblBacteria; ABC24310; ABC24310; Rru_A3516.
DR   KEGG; rru:Rru_A3516; -.
DR   PATRIC; fig|269796.9.peg.3633; -.
DR   eggNOG; ENOG5032SZ8; Bacteria.
DR   HOGENOM; CLU_149349_0_0_5; -.
DR   OMA; IDCDGNA; -.
DR   OrthoDB; 1880419at2; -.
DR   PhylomeDB; Q2RNI5; -.
DR   Proteomes; UP000001929; Chromosome.
DR   GO; GO:0071245; P:cellular response to carbon monoxide; IDA:UniProtKB.
DR   GO; GO:0071417; P:cellular response to organonitrogen compound; IDA:UniProtKB.
DR   GO; GO:0009399; P:nitrogen fixation; IMP:UniProtKB.
DR   HAMAP; MF_02117; CowN; 1.
DR   InterPro; IPR024899; CowN.
PE   1: Evidence at protein level;
KW   Nitrogen fixation; Reference proteome.
FT   CHAIN           1..101
FT                   /note="N(2)-fixation sustaining protein CowN"
FT                   /id="PRO_0000407273"
SQ   SEQUENCE   101 AA;  11357 MW;  62F064870AB03E1C CRC64;
     MTMDGPAHMP RRYVTFQGVN VEGLSQQLIA RILFHVADPA KSNAFWEHFK AKLADADKTL
     ARTADSLCLL CGAIGYIDEL FEDNDDEEGL TILRRLEDEL C