COX11_ARATH
ID COX11_ARATH Reviewed; 287 AA.
AC Q8GWR0; Q9FZ20;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Cytochrome c oxidase assembly protein COX11, mitochondrial;
DE Flags: Precursor;
GN Name=COX11; OrderedLocusNames=At1g02410; ORFNames=T6A9.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Exerts its effect at some terminal stage of cytochrome c
CC oxidase synthesis, probably by being involved in the insertion of the
CC copper B into subunit I. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}; Intermembrane side
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COX11/CtaG (TC 3.D.4.8) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG00893.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC064879; AAG00893.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27427.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59120.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59121.1; -; Genomic_DNA.
DR EMBL; AK118687; BAC43281.1; -; mRNA.
DR EMBL; BT005280; AAO63344.1; -; mRNA.
DR PIR; E86154; E86154.
DR RefSeq; NP_001321510.1; NM_001331337.1.
DR RefSeq; NP_001321511.1; NM_001331336.1.
DR RefSeq; NP_171743.1; NM_100122.6.
DR AlphaFoldDB; Q8GWR0; -.
DR SMR; Q8GWR0; -.
DR BioGRID; 24599; 2.
DR IntAct; Q8GWR0; 2.
DR STRING; 3702.AT1G02410.1; -.
DR PaxDb; Q8GWR0; -.
DR PRIDE; Q8GWR0; -.
DR ProteomicsDB; 240956; -.
DR DNASU; 839364; -.
DR EnsemblPlants; AT1G02410.1; AT1G02410.1; AT1G02410.
DR EnsemblPlants; AT1G02410.2; AT1G02410.2; AT1G02410.
DR EnsemblPlants; AT1G02410.3; AT1G02410.3; AT1G02410.
DR GeneID; 839364; -.
DR Gramene; AT1G02410.1; AT1G02410.1; AT1G02410.
DR Gramene; AT1G02410.2; AT1G02410.2; AT1G02410.
DR Gramene; AT1G02410.3; AT1G02410.3; AT1G02410.
DR KEGG; ath:AT1G02410; -.
DR Araport; AT1G02410; -.
DR TAIR; locus:2204838; AT1G02410.
DR eggNOG; KOG2540; Eukaryota.
DR HOGENOM; CLU_045000_1_2_1; -.
DR InParanoid; Q8GWR0; -.
DR OMA; YTHGACK; -.
DR OrthoDB; 1287401at2759; -.
DR PhylomeDB; Q8GWR0; -.
DR PRO; PR:Q8GWR0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8GWR0; baseline and differential.
DR Genevisible; Q8GWR0; AT.
DR GO; GO:0032592; C:integral component of mitochondrial membrane; IDA:TAIR.
DR GO; GO:0031304; C:intrinsic component of mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0043621; F:protein self-association; IDA:TAIR.
DR GO; GO:0009846; P:pollen germination; IMP:TAIR.
DR GO; GO:1904960; P:positive regulation of cytochrome-c oxidase activity; IMP:TAIR.
DR GO; GO:0010101; P:post-embryonic root morphogenesis; IMP:TAIR.
DR Gene3D; 2.60.370.10; -; 1.
DR HAMAP; MF_00155; CtaG; 1.
DR InterPro; IPR023471; CtaG/Cox11_dom_sf.
DR InterPro; IPR007533; Cyt_c_oxidase_assmbl_CtaG.
DR Pfam; PF04442; CtaG_Cox11; 1.
DR SUPFAM; SSF110111; SSF110111; 1.
PE 2: Evidence at transcript level;
KW Copper; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..80
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 81..287
FT /note="Cytochrome c oxidase assembly protein COX11,
FT mitochondrial"
FT /id="PRO_0000412526"
FT TOPO_DOM 81..92
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 116..287
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000255"
SQ SEQUENCE 287 AA; 32605 MW; 7221B3370A493F57 CRC64;
MSWSKACRGT RISSYLENLH RTSQYPRTIL CSRYYTHGAC KSNEHYLRSK RVFWGSSSSW
SLNSHSATAK SMLDSAHRQY STHSPSETKS QKMLYYLTAV VFGMVGLTYA AVPLYRTFCQ
ATGYGGTVQR KETVEEKIAR HSESGTVTER EIVVQFNADV ADGMQWKFTP TQREVRVKPG
ESALAFYTAE NKSSAPITGV STYNVTPMKA GVYFNKIQCF CFEEQRLLPG EQIDMPVFFY
IDPEFETDPR MDGINNLILS YTFFKVSEEN TTETVNNNNS VPVQETN
