ID   COX11_BOVIN             Reviewed;         282 AA.
AC   A3KMZ6;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Cytochrome c oxidase assembly protein COX11, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX11;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exerts its effect at some terminal stage of cytochrome c
CC       oxidase synthesis, probably by being involved in the insertion of the
CC       copper B into subunit I. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with CNNM4/ACDP4. Interacts with RANBP2.
CC       {ECO:0000250|UniProtKB:Q9Y6N1}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9Y6N1}; Single-pass membrane protein
CC       {ECO:0000255}; Intermembrane side {ECO:0000250|UniProtKB:Q9Y6N1}.
CC   -!- SIMILARITY: Belongs to the COX11/CtaG family. {ECO:0000305}.
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DR   EMBL; BC133444; AAI33445.1; -; mRNA.
DR   RefSeq; NP_001076872.1; NM_001083403.2.
DR   AlphaFoldDB; A3KMZ6; -.
DR   SMR; A3KMZ6; -.
DR   STRING; 9913.ENSBTAP00000009231; -.
DR   PaxDb; A3KMZ6; -.
DR   Ensembl; ENSBTAT00000009231; ENSBTAP00000009231; ENSBTAG00000007015.
DR   GeneID; 510509; -.
DR   KEGG; bta:510509; -.
DR   CTD; 1353; -.
DR   VEuPathDB; HostDB:ENSBTAG00000007015; -.
DR   VGNC; VGNC:55805; COX11.
DR   eggNOG; KOG2540; Eukaryota.
DR   GeneTree; ENSGT00390000007512; -.
DR   InParanoid; A3KMZ6; -.
DR   OMA; NKLECFC; -.
DR   OrthoDB; 1287401at2759; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000007015; Expressed in rumen papilla and 103 other tissues.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0031304; C:intrinsic component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0055065; P:metal ion homeostasis; IEA:Ensembl.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; IEA:Ensembl.
DR   Gene3D; 2.60.370.10; -; 1.
DR   HAMAP; MF_00155; CtaG; 1.
DR   InterPro; IPR023471; CtaG/Cox11_dom_sf.
DR   InterPro; IPR007533; Cyt_c_oxidase_assmbl_CtaG.
DR   Pfam; PF04442; CtaG_Cox11; 1.
DR   SUPFAM; SSF110111; SSF110111; 1.
PE   2: Evidence at transcript level;
KW   Copper; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..282
FT                   /note="Cytochrome c oxidase assembly protein COX11,
FT                   mitochondrial"
FT                   /id="PRO_0000311197"
FT   TOPO_DOM        29..90
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y6N1"
FT   TRANSMEM        91..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        110..282
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y6N1"
FT   REGION          28..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   282 AA;  31824 MW;  BEB4CDBBC497A551 CRC64;
     MGGLWRPAWR RVVFCGWSWS HLGRPTRAAE RAEPCLRPGR SGPAGTEQGL RRLGTWRRPS
     PAEQPARRPK STNPYTRSQE EDWRRRNKTV LTYMAAAAVG MLGASYAAVP LYRLYCQTTG
     LGGSAVAGHA SDQIENMVPV KDRIIKITFN ADVHASLQWN FRPQQTEIYV VPGETALAFY
     KAKNPTDKPV IGISTYNVVP FEAGQYFNKI QCFCFEEQRL NPQEEVDMPV FFYIDPEFAE
     DPRMVNVDLI TLSYTFFEAK EGHTLPVPGY NSNQQLSPAS NL