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COX11_PONAB
ID   COX11_PONAB             Reviewed;         277 AA.
AC   Q5R7U6;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Cytochrome c oxidase assembly protein COX11, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX11;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exerts its effect at some terminal stage of cytochrome c
CC       oxidase synthesis, probably by being involved in the insertion of the
CC       copper B into subunit I. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with CNNM4/ACDP4. Interacts with RANBP2.
CC       {ECO:0000250|UniProtKB:Q9Y6N1}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9Y6N1}; Single-pass membrane protein
CC       {ECO:0000255}; Intermembrane side {ECO:0000250|UniProtKB:Q9Y6N1}.
CC   -!- SIMILARITY: Belongs to the COX11/CtaG family. {ECO:0000305}.
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DR   EMBL; CR860013; CAH92164.1; ALT_TERM; Transcribed_RNA.
DR   AlphaFoldDB; Q5R7U6; -.
DR   SMR; Q5R7U6; -.
DR   STRING; 9601.ENSPPYP00000009281; -.
DR   eggNOG; KOG2540; Eukaryota.
DR   InParanoid; Q5R7U6; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   Gene3D; 2.60.370.10; -; 1.
DR   HAMAP; MF_00155; CtaG; 1.
DR   InterPro; IPR023471; CtaG/Cox11_dom_sf.
DR   InterPro; IPR007533; Cyt_c_oxidase_assmbl_CtaG.
DR   Pfam; PF04442; CtaG_Cox11; 1.
DR   SUPFAM; SSF110111; SSF110111; 1.
PE   3: Inferred from homology;
KW   Copper; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..277
FT                   /note="Cytochrome c oxidase assembly protein COX11,
FT                   mitochondrial"
FT                   /id="PRO_0000042180"
FT   TOPO_DOM        29..94
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y6N1"
FT   TRANSMEM        95..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        118..277
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y6N1"
FT   REGION          64..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   277 AA;  31455 MW;  38A4CC0E35FF051A CRC64;
     MGGLWRPGWR RVAFCGWRWI HPGSPTRAAE RVEPFLRPEC SGTGGAGRGL RWLGTWKRCS
     LGARHPALQP PRRHKNSNPF TRAQKEEWRR RNKTTLTYVA AVAVGMLGAS YAAVPLYRLY
     CQTTGLGGSA VAGHASDKIE NMVPVKDRII KISFNADVHA SLQWNFRPQQ TEIYVVPGET
     ALAFYRAKNP TDKPVIGIST YNIVPFEAGQ YFNKIQQCFC FEEQRLNPQE EVDMPVFFYI
     DPEFAEDPRM IKVDLITLSY TFFEAKEGHK LPVPGYN
 
 
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