COX14_BOVIN
ID COX14_BOVIN Reviewed; 57 AA.
AC Q1RMH3;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Cytochrome c oxidase assembly protein COX14;
GN Name=COX14;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal skin;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Core component of the MITRAC (mitochondrial translation
CC regulation assembly intermediate of cytochrome c oxidase complex)
CC complex, that regulates cytochrome c oxidase assembly. Requires for
CC coordination of the early steps of cytochrome c oxidase assembly with
CC the synthesis of MT-CO1. {ECO:0000250|UniProtKB:Q96I36}.
CC -!- SUBUNIT: Along with COA3, core component of the MITRAC (mitochondrial
CC translation regulation assembly intermediate of cytochrome c oxidase
CC complex) complex. {ECO:0000250|UniProtKB:Q96I36}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC membrane protein {ECO:0000250}.
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DR EMBL; BC114898; AAI14899.1; -; mRNA.
DR RefSeq; NP_001181993.1; NM_001195064.1.
DR RefSeq; XP_005206389.1; XM_005206332.3.
DR RefSeq; XP_010803296.1; XM_010804994.2.
DR RefSeq; XP_015326481.1; XM_015470995.1.
DR RefSeq; XP_015326482.1; XM_015470996.1.
DR RefSeq; XP_015326483.1; XM_015470997.1.
DR AlphaFoldDB; Q1RMH3; -.
DR STRING; 9913.ENSBTAP00000001069; -.
DR PaxDb; Q1RMH3; -.
DR PRIDE; Q1RMH3; -.
DR Ensembl; ENSBTAT00000001069; ENSBTAP00000001069; ENSBTAG00000000808.
DR GeneID; 768048; -.
DR KEGG; bta:768048; -.
DR CTD; 84987; -.
DR VEuPathDB; HostDB:ENSBTAG00000000808; -.
DR VGNC; VGNC:27628; COX14.
DR eggNOG; ENOG502SCZ6; Eukaryota.
DR GeneTree; ENSGT00390000002190; -.
DR HOGENOM; CLU_209431_0_0_1; -.
DR InParanoid; Q1RMH3; -.
DR OMA; VYHYFQR; -.
DR OrthoDB; 1641370at2759; -.
DR TreeFam; TF338398; -.
DR Reactome; R-BTA-5628897; TP53 Regulates Metabolic Genes.
DR Reactome; R-BTA-611105; Respiratory electron transport.
DR Reactome; R-BTA-9707564; Cytoprotection by HMOX1.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000000808; Expressed in diaphragm and 104 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISS:UniProtKB.
DR InterPro; IPR029208; COX14.
DR PANTHER; PTHR36684; PTHR36684; 1.
DR Pfam; PF14880; COX14; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..57
FT /note="Cytochrome c oxidase assembly protein COX14"
FT /id="PRO_0000263676"
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 57 AA; 6470 MW; 5AE18B4A78C83382 CRC64;
MPTAKQLADI GYKTFSTSMM LLTVYGGYLC SVRAYHYFQR RSSRRQAAEE QKTSGAL