ID   COX14_RAT               Reviewed;          57 AA.
AC   Q5XFV8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Cytochrome c oxidase assembly protein COX14;
GN   Name=Cox14;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Core component of the MITRAC (mitochondrial translation
CC       regulation assembly intermediate of cytochrome c oxidase complex)
CC       complex, that regulates cytochrome c oxidase assembly. Requires for
CC       coordination of the early steps of cytochrome c oxidase assembly with
CC       the synthesis of MT-CO1. {ECO:0000250|UniProtKB:Q96I36}.
CC   -!- SUBUNIT: Along with COA3, core component of the MITRAC (mitochondrial
CC       translation regulation assembly intermediate of cytochrome c oxidase
CC       complex) complex. {ECO:0000250|UniProtKB:Q96I36}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
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DR   EMBL; BC084716; AAH84716.1; -; mRNA.
DR   RefSeq; XP_001060794.2; XM_001060794.6.
DR   RefSeq; XP_002727019.1; XM_002726973.5.
DR   AlphaFoldDB; Q5XFV8; -.
DR   SMR; Q5XFV8; -.
DR   STRING; 10116.ENSRNOP00000035841; -.
DR   PaxDb; Q5XFV8; -.
DR   PRIDE; Q5XFV8; -.
DR   GeneID; 681219; -.
DR   UCSC; RGD:1598052; rat.
DR   CTD; 84987; -.
DR   RGD; 1598052; Cox14.
DR   eggNOG; ENOG502SCZ6; Eukaryota.
DR   HOGENOM; CLU_209431_0_0_1; -.
DR   InParanoid; Q5XFV8; -.
DR   OMA; VYHYFQR; -.
DR   OrthoDB; 1641370at2759; -.
DR   PhylomeDB; Q5XFV8; -.
DR   TreeFam; TF338398; -.
DR   Reactome; R-RNO-5628897; TP53 Regulates Metabolic Genes.
DR   Reactome; R-RNO-611105; Respiratory electron transport.
DR   Reactome; R-RNO-9707564; Cytoprotection by HMOX1.
DR   PRO; PR:Q5XFV8; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000061425; Expressed in frontal cortex and 20 other tissues.
DR   Genevisible; Q5XFV8; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISS:UniProtKB.
DR   InterPro; IPR029208; COX14.
DR   PANTHER; PTHR36684; PTHR36684; 1.
DR   Pfam; PF14880; COX14; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..57
FT                   /note="Cytochrome c oxidase assembly protein COX14"
FT                   /id="PRO_0000263679"
FT   TRANSMEM        15..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   57 AA;  6361 MW;  4BEE2BF615A82008 CRC64;
     MPSAKQLADI GYKTFSASMM LLTVYGGYLC SVRAYHYLQL RSARRQAAEE QKTSGVL