ID   COX16_ASHGO             Reviewed;         121 AA.
AC   Q75FA7;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Cytochrome c oxidase assembly protein COX16, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX16; OrderedLocusNames=AAL168C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Required for the assembly of the mitochondrial respiratory
CC       chain complex IV (CIV), also known as cytochrome c oxidase. May
CC       participate in merging the COX1 and COX2 assembly lines.
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P47081}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SIMILARITY: Belongs to the COX16 family. {ECO:0000305}.
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DR   EMBL; AE016814; AAS50198.1; -; Genomic_DNA.
DR   RefSeq; NP_982374.1; NM_207727.1.
DR   AlphaFoldDB; Q75FA7; -.
DR   STRING; 33169.AAS50198; -.
DR   PRIDE; Q75FA7; -.
DR   EnsemblFungi; AAS50198; AAS50198; AGOS_AAL168C.
DR   GeneID; 4618435; -.
DR   KEGG; ago:AGOS_AAL168C; -.
DR   eggNOG; ENOG502S9GT; Eukaryota.
DR   HOGENOM; CLU_131611_2_0_1; -.
DR   InParanoid; Q75FA7; -.
DR   OMA; FMLTPAT; -.
DR   Proteomes; UP000000591; Chromosome I.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IBA:GO_Central.
DR   InterPro; IPR020164; Cyt_c_Oxase_assmbl_COX16.
DR   Pfam; PF14138; COX16; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..31
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..121
FT                   /note="Cytochrome c oxidase assembly protein COX16,
FT                   mitochondrial"
FT                   /id="PRO_0000280639"
FT   TRANSMEM        34..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   121 AA;  14287 MW;  CE9605CC50699BB7 CRC64;
     MSLGSRTFRS KRQMAAFEKS LQGRYLKLLR RNPFLFYGVP FCTLMAVGSY CLSDFTAVKY
     EREDKKVRSV QEDELVKLRA NRRTVDLKEE FYRLQGLADQ DWEPVRVPRL PGESENVWDV
     E