ID   COX16_ASPCL             Reviewed;         134 AA.
AC   A1C8Z3;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 2.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Cytochrome c oxidase assembly protein cox16, mitochondrial;
DE   Flags: Precursor;
GN   Name=cox16; ORFNames=ACLA_053630;
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Required for the assembly of the mitochondrial respiratory
CC       chain complex IV (CIV), also known as cytochrome c oxidase. May
CC       participate in merging the COX1 and COX2 assembly lines.
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P47081}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SIMILARITY: Belongs to the COX16 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAW13317.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; DS027048; EAW13317.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_001274743.1; XM_001274742.1.
DR   AlphaFoldDB; A1C8Z3; -.
DR   STRING; 5057.CADACLAP00005183; -.
DR   EnsemblFungi; EAW13317; EAW13317; ACLA_053630.
DR   GeneID; 4706973; -.
DR   KEGG; act:ACLA_053630; -.
DR   eggNOG; ENOG502S9GT; Eukaryota.
DR   OrthoDB; 1550606at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR020164; Cyt_c_Oxase_assmbl_COX16.
DR   Pfam; PF14138; COX16; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..23
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..134
FT                   /note="Cytochrome c oxidase assembly protein cox16,
FT                   mitochondrial"
FT                   /id="PRO_0000280640"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   134 AA;  15359 MW;  6C69BCF6200C8D25 CRC64;
     MPVFQAKTFR RATTASSSLG ERIGAAYRGG LPKHPFLLFG LPFIMVIVAG SFVLTPAAAL
     RYERYDRKVK QLSQEEAMEL GLKGPDGEEG IRRNPRRRIL GDEREEYYRL MAKDLDNWEQ
     KRVQRFKGEP DGKL