ID   COX16_CANGA             Reviewed;         118 AA.
AC   Q6FW43;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Cytochrome c oxidase assembly protein COX16, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX16; OrderedLocusNames=CAGL0D03102g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the assembly of the mitochondrial respiratory
CC       chain complex IV (CIV), also known as cytochrome c oxidase. May
CC       participate in merging the COX1 and COX2 assembly lines.
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P47081}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P47081}.
CC   -!- SIMILARITY: Belongs to the COX16 family. {ECO:0000305}.
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DR   EMBL; CR380950; CAG58462.1; -; Genomic_DNA.
DR   RefSeq; XP_445551.1; XM_445551.1.
DR   AlphaFoldDB; Q6FW43; -.
DR   SMR; Q6FW43; -.
DR   STRING; 5478.XP_445551.1; -.
DR   EnsemblFungi; CAG58462; CAG58462; CAGL0D03102g.
DR   GeneID; 2886982; -.
DR   KEGG; cgr:CAGL0D03102g; -.
DR   CGD; CAL0128271; CAGL0D03102g.
DR   VEuPathDB; FungiDB:CAGL0D03102g; -.
DR   eggNOG; ENOG502S9GT; Eukaryota.
DR   HOGENOM; CLU_131611_2_0_1; -.
DR   InParanoid; Q6FW43; -.
DR   OMA; FMLTPAT; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:EnsemblFungi.
DR   InterPro; IPR020164; Cyt_c_Oxase_assmbl_COX16.
DR   Pfam; PF14138; COX16; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..118
FT                   /note="Cytochrome c oxidase assembly protein COX16,
FT                   mitochondrial"
FT                   /id="PRO_0000280643"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   118 AA;  14019 MW;  20DB98C926265A7C CRC64;
     MALGGRSFRS KKQQLAYDRS FAGRYQKLLS KNPFIFFGLP FCGMMVLGSY WLAGISQVKF
     DRDDQKVQEM NEEEILKMKH GKREFDIKEE YYRLQGLAEE DWEPKRVERF KGESDNVF