COX19_ASHGO
ID COX19_ASHGO Reviewed; 99 AA.
AC Q75AF9;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 2.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Cytochrome c oxidase assembly protein COX19;
GN Name=COX19; OrderedLocusNames=ADL041C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 6; 17; 21; 33 AND 56.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Required for the assembly of mitochondrial cytochrome c
CC oxidase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion
CC intermembrane space {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COX19 family. {ECO:0000305}.
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DR EMBL; AE016817; AAS51879.2; -; Genomic_DNA.
DR RefSeq; NP_984055.2; NM_209408.2.
DR AlphaFoldDB; Q75AF9; -.
DR SMR; Q75AF9; -.
DR STRING; 33169.AAS51879; -.
DR EnsemblFungi; AAS51879; AAS51879; AGOS_ADL041C.
DR GeneID; 4620203; -.
DR KEGG; ago:AGOS_ADL041C; -.
DR eggNOG; KOG3477; Eukaryota.
DR HOGENOM; CLU_141947_3_1_1; -.
DR InParanoid; Q75AF9; -.
DR OMA; LECRMDN; -.
DR Proteomes; UP000000591; Chromosome IV.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR GO; GO:0005507; F:copper ion binding; IEA:EnsemblFungi.
DR GO; GO:0030001; P:metal ion transport; IEA:EnsemblFungi.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IBA:GO_Central.
DR PROSITE; PS51808; CHCH; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Disulfide bond; Mitochondrion; Reference proteome.
FT CHAIN 1..99
FT /note="Cytochrome c oxidase assembly protein COX19"
FT /id="PRO_0000122284"
FT DOMAIN 27..70
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 30..40
FT /note="Cx9C motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 52..62
FT /note="Cx9C motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 30..62
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 40..52
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 99 AA; 11038 MW; E08B8938DF0A6EFE CRC64;
MSGNPGSALQ ALSPTPPERG SFPLDHEGEC TAQMMEYLNC MKLVRGENAP NCRLLARNYL
KCRMDHRLMD RDEWAHLGLP DDKRAEAAAS ADSARPPRQ
