ID   COX23_ASHGO             Reviewed;         111 AA.
AC   Q75D94;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 2.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Cytochrome c oxidase-assembly factor COX23, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX23; OrderedLocusNames=ABR130W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION, AND SEQUENCE REVISION TO 43; 52 AND 61.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Required for the assembly of cytochrome c oxidase.
CC       {ECO:0000250|UniProtKB:P38824}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COX23 family. {ECO:0000305}.
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DR   EMBL; AE016815; AAS50901.2; -; Genomic_DNA.
DR   RefSeq; NP_983077.2; NM_208430.2.
DR   AlphaFoldDB; Q75D94; -.
DR   SMR; Q75D94; -.
DR   STRING; 33169.AAS50901; -.
DR   EnsemblFungi; AAS50901; AAS50901; AGOS_ABR130W.
DR   GeneID; 4619185; -.
DR   KEGG; ago:AGOS_ABR130W; -.
DR   eggNOG; KOG4618; Eukaryota.
DR   HOGENOM; CLU_153383_1_0_1; -.
DR   InParanoid; Q75D94; -.
DR   OMA; DPCQESS; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0033108; P:mitochondrial respiratory chain complex assembly; IBA:GO_Central.
DR   InterPro; IPR010625; CHCH.
DR   InterPro; IPR009069; Cys_alpha_HP_mot_SF.
DR   Pfam; PF06747; CHCH; 1.
DR   SUPFAM; SSF47072; SSF47072; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..111
FT                   /note="Cytochrome c oxidase-assembly factor COX23,
FT                   mitochondrial"
FT                   /id="PRO_0000280655"
FT   DOMAIN          61..103
FT                   /note="CHCH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           64..74
FT                   /note="Cx9C motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           85..95
FT                   /note="Cx9C motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        64..95
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        74..85
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ   SEQUENCE   111 AA;  12793 MW;  FC17949FE7B962A0 CRC64;
     MPVDTAAPQS TANPDPSVQT DRAAVNFTPS TDASSFQFYP DNPESPLARY RFAAKGPSQY
     FDPCQESANM SMKCLERNNY DRDLCREYFD AYRECKKQWL SARRKDNSQW T