COX23_ASPCL
ID COX23_ASPCL Reviewed; 88 AA.
AC A1CH57;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Cytochrome c oxidase-assembly factor cox23, mitochondrial;
DE Flags: Precursor;
GN Name=cox23; ORFNames=ACLA_046780;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Required for the assembly of cytochrome c oxidase.
CC {ECO:0000250|UniProtKB:P38824}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COX23 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAW10212.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DS027054; EAW10212.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_001271638.1; XM_001271637.1.
DR AlphaFoldDB; A1CH57; -.
DR SMR; A1CH57; -.
DR STRING; 344612.A1CH57; -.
DR GeneID; 4704404; -.
DR KEGG; act:ACLA_046780; -.
DR OrthoDB; 1617584at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR InterPro; IPR009069; Cys_alpha_HP_mot_SF.
DR SUPFAM; SSF47072; SSF47072; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Mitochondrion; Reference proteome; Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..88
FT /note="Cytochrome c oxidase-assembly factor cox23,
FT mitochondrial"
FT /id="PRO_0000280656"
FT DOMAIN 43..85
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 46..56
FT /note="Cx9C motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 67..77
FT /note="Cx9C motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 46..77
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 56..67
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 88 AA; 10450 MW; 39442A1EA6CC6AE6 CRC64;
MASQSSQADQ QQQQQQQSSQ SQQPNAWEKA ERKFANKNAS EYYDPCQDFA DRSLKCMKRN
AFDKEMCGDY FQAYRDCKKQ WLTQKKFS
