ID   COX23_CANGA             Reviewed;         111 AA.
AC   Q6FQX5;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Cytochrome c oxidase-assembly factor COX23, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX23; OrderedLocusNames=CAGL0I02728g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the assembly of cytochrome c oxidase.
CC       {ECO:0000250|UniProtKB:P38824}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COX23 family. {ECO:0000305}.
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DR   EMBL; CR380955; CAG60306.1; -; Genomic_DNA.
DR   RefSeq; XP_447369.1; XM_447369.1.
DR   AlphaFoldDB; Q6FQX5; -.
DR   SMR; Q6FQX5; -.
DR   STRING; 5478.XP_447369.1; -.
DR   EnsemblFungi; CAG60306; CAG60306; CAGL0I02728g.
DR   GeneID; 2889023; -.
DR   KEGG; cgr:CAGL0I02728g; -.
DR   CGD; CAL0132672; CAGL0I02728g.
DR   VEuPathDB; FungiDB:CAGL0I02728g; -.
DR   eggNOG; KOG4618; Eukaryota.
DR   HOGENOM; CLU_153383_1_0_1; -.
DR   InParanoid; Q6FQX5; -.
DR   OMA; DPCQESS; -.
DR   Proteomes; UP000002428; Chromosome I.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR   GO; GO:0033108; P:mitochondrial respiratory chain complex assembly; IEA:EnsemblFungi.
DR   InterPro; IPR009069; Cys_alpha_HP_mot_SF.
DR   SUPFAM; SSF47072; SSF47072; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..111
FT                   /note="Cytochrome c oxidase-assembly factor COX23,
FT                   mitochondrial"
FT                   /id="PRO_0000280658"
FT   DOMAIN          61..103
FT                   /note="CHCH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           64..74
FT                   /note="Cx9C motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           85..95
FT                   /note="Cx9C motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        64..95
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        74..85
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ   SEQUENCE   111 AA;  13439 MW;  06A2F519CBB1288B CRC64;
     MAADEDIIKD GNYDPHVQTD KDKVDYAPKG VDTTEYRYYP DNPESTLNKY RFAMKDHSQY
     YDPCQESAKM SFKCLELNDY DRDQCKEYFD AYRECKKQWL EARRKDRTNW S