ID   COX4_BACP3              Reviewed;         110 AA.
AC   Q03440;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Cytochrome c oxidase subunit 4B;
DE            EC=7.1.1.9;
DE   AltName: Full=Cytochrome aa3 subunit 4B;
DE   AltName: Full=Cytochrome c oxidase polypeptide IVB;
GN   Name=caaD;
OS   Bacillus sp. (strain PS3).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-17.
RX   PubMed=1964459; DOI=10.1093/oxfordjournals.jbchem.a123294;
RA   Ishizuka M., Machida K., Shimada S., Mogi A., Tsuchiya T., Ohmori T.,
RA   Souma Y., Gonda M., Sone N.;
RT   "Nucleotide sequence of the gene coding for four subunits of cytochrome c
RT   oxidase from the thermophilic bacterium PS3.";
RL   J. Biochem. 108:866-873(1990).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-
CC         [cytochrome c] + 4 H(+)(out) + 2 H2O; Xref=Rhea:RHEA:11436,
CC         Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:29033,
CC         ChEBI:CHEBI:29034; EC=7.1.1.9;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC       family. {ECO:0000305}.
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DR   EMBL; D13955; BAA03048.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q03440; -.
DR   SMR; Q03440; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR014257; Cyt_c_oxidase_su4_bacillaceae.
DR   InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR   Pfam; PF03626; COX4_pro; 1.
DR   TIGRFAMs; TIGR02908; CoxD_Bacillus; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Membrane; Translocase;
KW   Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:1964459"
FT   CHAIN           2..110
FT                   /note="Cytochrome c oxidase subunit 4B"
FT                   /id="PRO_0000183901"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   110 AA;  12864 MW;  04A68F25EF2EABB4 CRC64;
     MANQTNSGNE RVDLAYRRRK NAEEMRHQMI AFVLMILLTL IAFAAVGYEE FSHWFVVPFI
     LLLAAVQVAF QLYYFMHMSH KGHEFPAMFI YGGVAVMLLL VWAFTTVVWW