ID   COX5C_IPOBA             Reviewed;          64 AA.
AC   P19173;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Cytochrome c oxidase subunit 5C;
DE   AltName: Full=Cytochrome c oxidase polypeptide Vc;
GN   Name=COX5C; Synonyms=COXVC;
OS   Ipomoea batatas (Sweet potato) (Convolvulus batatas).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea.
OX   NCBI_TaxID=4120;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Kokei No. 14; TISSUE=Tuberous root;
RX   PubMed=2167844; DOI=10.1111/j.1432-1033.1990.tb19157.x;
RA   Nakagawa T., Maeshima M., Nakamura K., Asahi T.;
RT   "Molecular cloning of a cDNA for the smallest nuclear-encoded subunit of
RT   sweet potato cytochrome c oxidase. Analysis with the cDNA of the structure
RT   and import into mitochondria of the subunit.";
RL   Eur. J. Biochem. 191:557-561(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. Kokei No. 14;
RX   PubMed=8025826;
RA   Nakagawa T., Maeshima M., Nakamura K., Asahi T.;
RT   "The nuclear gene for subunit Vc of sweet potato cytochrome c oxidase.";
RL   Plant Cell Physiol. 34:621-626(1993).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-26.
RC   STRAIN=cv. Kokei No. 14; TISSUE=Tuberous root;
RX   PubMed=2885192; DOI=10.1111/j.1432-1033.1987.tb11442.x;
RA   Nakagawa T., Maeshima M., Muto H., Kajiura H., Hattori H., Asahi T.;
RT   "Separation, amino-terminal sequence and cell-free synthesis of the
RT   smallest subunit of sweet potato cytochrome c oxidase.";
RL   Eur. J. Biochem. 165:303-307(1987).
CC   -!- FUNCTION: This protein is one of the nuclear-coded polypeptide chains
CC       of cytochrome c oxidase, the terminal oxidase in mitochondrial electron
CC       transport.
CC   -!- SUBUNIT: Sweet potato cytochrome C oxidase consists of at least seven
CC       different polypeptides species, subunits I, II, III, IV, Va, Vb, and Vc
CC       in order of MW.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane.
CC   -!- MISCELLANEOUS: This precursor was imported into isolated sweet potato
CC       tuberous root mitochondria without any significant processing, the
CC       import being dependent on membrane potential.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 5C family.
CC       {ECO:0000305}.
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DR   EMBL; X53393; CAA37470.1; -; mRNA.
DR   EMBL; S73602; AAB31231.1; -; Genomic_DNA.
DR   PIR; S09297; S09297.
DR   PIR; S11029; S11029.
DR   AlphaFoldDB; P19173; -.
DR   SMR; P19173; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005746; C:mitochondrial respirasome; IEA:InterPro.
DR   InterPro; IPR008432; COX5C.
DR   PANTHER; PTHR34372; PTHR34372; 1.
DR   PIRSF; PIRSF038131; COX5C; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:2885192"
FT   CHAIN           2..64
FT                   /note="Cytochrome c oxidase subunit 5C"
FT                   /id="PRO_0000128192"
FT   TRANSMEM        16..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   64 AA;  7172 MW;  7ACEC88A09F4F0B0 CRC64;
     MAGGHVAHLV YKGPSVVKEL VIGFSLGLVA GGFWKMHHWN SQRRTKEFYD MLEKGQISVV
     ADEE