COX7R_BOVIN
ID COX7R_BOVIN Reviewed; 114 AA.
AC Q3T061;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Cytochrome c oxidase subunit 7A-related protein, mitochondrial;
DE AltName: Full=Cytochrome c oxidase subunit VIIa-related protein;
DE Flags: Precursor;
GN Name=COX7A2L;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the regulation of oxidative phosphorylation and
CC energy metabolism (By similarity). Necessary for the assembly of
CC mitochondrial respiratory supercomplex (By similarity).
CC {ECO:0000250|UniProtKB:Q61387}.
CC -!- SUBUNIT: Interacts with the mitochondrial respiratory supercomplex.
CC {ECO:0000250|UniProtKB:Q61387}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase VIIa family.
CC {ECO:0000305}.
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DR EMBL; BC102552; AAI02553.1; -; mRNA.
DR RefSeq; NP_001029867.1; NM_001034695.2.
DR AlphaFoldDB; Q3T061; -.
DR SMR; Q3T061; -.
DR STRING; 9913.ENSBTAP00000000943; -.
DR PaxDb; Q3T061; -.
DR PeptideAtlas; Q3T061; -.
DR PRIDE; Q3T061; -.
DR Ensembl; ENSBTAT00000000943; ENSBTAP00000000943; ENSBTAG00000000705.
DR GeneID; 540225; -.
DR KEGG; bta:540225; -.
DR CTD; 9167; -.
DR VEuPathDB; HostDB:ENSBTAG00000000705; -.
DR VGNC; VGNC:27640; COX7A2L.
DR eggNOG; ENOG502S14M; Eukaryota.
DR GeneTree; ENSGT00940000154815; -.
DR HOGENOM; CLU_149431_0_0_1; -.
DR InParanoid; Q3T061; -.
DR OMA; YPKYDYA; -.
DR OrthoDB; 1548349at2759; -.
DR TreeFam; TF105067; -.
DR Reactome; R-BTA-5628897; TP53 Regulates Metabolic Genes.
DR Reactome; R-BTA-611105; Respiratory electron transport.
DR Reactome; R-BTA-9707564; Cytoprotection by HMOX1.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000000705; Expressed in oocyte and 107 other tissues.
DR GO; GO:0005746; C:mitochondrial respirasome; ISS:UniProtKB.
DR GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IEA:InterPro.
DR GO; GO:0097250; P:mitochondrial respirasome assembly; ISS:UniProtKB.
DR GO; GO:0002082; P:regulation of oxidative phosphorylation; ISS:UniProtKB.
DR CDD; cd00928; Cyt_c_Oxidase_VIIa; 1.
DR Gene3D; 4.10.91.10; -; 1.
DR InterPro; IPR039297; COX7a.
DR InterPro; IPR017267; Cyt_c_oxidase_su7a-rel_mt.
DR InterPro; IPR036539; Cyt_c_oxidase_su7a_sf.
DR InterPro; IPR003177; Cytc_oxidase_su7a_met.
DR PANTHER; PTHR10510; PTHR10510; 1.
DR PANTHER; PTHR10510:SF2; PTHR10510:SF2; 1.
DR Pfam; PF02238; COX7a; 1.
DR PIRSF; PIRSF037710; COX7A-rel_mt; 1.
DR SUPFAM; SSF81419; SSF81419; 1.
PE 3: Inferred from homology;
KW Acetylation; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Transit peptide.
FT TRANSIT 1..55
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 56..114
FT /note="Cytochrome c oxidase subunit 7A-related protein,
FT mitochondrial"
FT /id="PRO_0000247326"
FT MOD_RES 69
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:O14548"
SQ SEQUENCE 114 AA; 12544 MW; 953BC55FD65E379F CRC64;
MYYKFSGFTQ KLAGAWASDA YSPQGLRPVV STEAPPIIFA TPTKLSSGPT AYDYAGKNTV
PELQKFFQKS DGVPIHLKRG LPDQMLYRTT MALTVGGTIY CLIALYMASQ PRNK
