ID   COX7S_HUMAN             Reviewed;         106 AA.
AC   O60397;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Putative cytochrome c oxidase subunit 7A3, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa 3;
DE   Flags: Precursor;
GN   Name=COX7A2P2; Synonyms=COX7A3, COX7AL2, COX7AP2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase VIIa family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC004544; AAC12952.1; -; Genomic_DNA.
DR   AlphaFoldDB; O60397; -.
DR   SMR; O60397; -.
DR   BioMuta; HGNC:2290; -.
DR   MassIVE; O60397; -.
DR   PeptideAtlas; O60397; -.
DR   PRIDE; O60397; -.
DR   TopDownProteomics; O60397; -.
DR   GeneCards; COX7A2P2; -.
DR   HGNC; HGNC:2290; COX7A2P2.
DR   MIM; 123997; gene.
DR   neXtProt; NX_O60397; -.
DR   InParanoid; O60397; -.
DR   PhylomeDB; O60397; -.
DR   PathwayCommons; O60397; -.
DR   Pharos; O60397; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; O60397; protein.
DR   GO; GO:0005746; C:mitochondrial respirasome; IBA:GO_Central.
DR   GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:InterPro.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IEA:InterPro.
DR   GO; GO:0097250; P:mitochondrial respirasome assembly; IBA:GO_Central.
DR   GO; GO:0002082; P:regulation of oxidative phosphorylation; IBA:GO_Central.
DR   CDD; cd00928; Cyt_c_Oxidase_VIIa; 1.
DR   Gene3D; 4.10.91.10; -; 1.
DR   InterPro; IPR039297; COX7a.
DR   InterPro; IPR036539; Cyt_c_oxidase_su7a_sf.
DR   InterPro; IPR003177; Cytc_oxidase_su7a_met.
DR   PANTHER; PTHR10510; PTHR10510; 1.
DR   Pfam; PF02238; COX7a; 1.
DR   SUPFAM; SSF81419; SSF81419; 1.
PE   5: Uncertain;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..23
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           24..106
FT                   /note="Putative cytochrome c oxidase subunit 7A3,
FT                   mitochondrial"
FT                   /id="PRO_0000006156"
SQ   SEQUENCE   106 AA;  11841 MW;  B4844D79738FDFE7 CRC64;
     MLWNLLALHQ IGQRTISTAS HRHFKNKVPE KQKLFQEDDG IPLYLKGGIA DALLHRATMI
     LTVGGTAYAI YQLAVASFPN KGVTSIIPAI TWFTFIQLSM DQKSDK