COXA_BACSU
ID COXA_BACSU Reviewed; 198 AA.
AC P94446; O32061;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 14-APR-2009, sequence version 4.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Sporulation cortex protein CoxA;
DE Flags: Precursor;
GN Name=coxA; Synonyms=yrbB; OrderedLocusNames=BSU27830;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RC STRAIN=168 / 60015;
RX PubMed=9770294; DOI=10.1111/j.1574-6968.1998.tb13913.x;
RA Takamatsu H., Hiraoka T., Kodama T., Koide H., Kozuka S., Tochikubo K.,
RA Watabe K.;
RT "Cloning of a novel gene yrbB, encoding a protein located in the spore
RT integument of Bacillus subtilis.";
RL FEMS Microbiol. Lett. 166:361-367(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Tosato V., Bolotin A., Bertani I., Valentino I., Bruschi C.V.;
RT "A 17.8 kb segment in the spoVB-nadC region of the Bacillus subtilis 168
RT chromosome: sequencing and ruv operon identification.";
RL Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP TRANSCRIPTION.
RC STRAIN=168;
RX PubMed=10438771; DOI=10.1128/jb.181.16.4986-4994.1999;
RA Takamatsu H., Kodama T., Nakayama T., Watabe K.;
RT "Characterization of the yrbA gene of Bacillus subtilis, involved in
RT resistance and germination of spores.";
RL J. Bacteriol. 181:4986-4994(1999).
CC -!- SUBCELLULAR LOCATION: Spore cortex {ECO:0000269|PubMed:9770294}.
CC Note=Within the spore integument, mainly in the cortex layer with a
CC part in the inner region of the coat layer.
CC -!- INDUCTION: Transcribed by SigG at time T3 of sporulation.
CC -!- MISCELLANEOUS: Present in spore but not in vegetative cell.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA24944.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB75323.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; D50551; BAA24944.1; ALT_INIT; Genomic_DNA.
DR EMBL; Y15896; CAB75323.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB14743.2; -; Genomic_DNA.
DR PIR; A69972; A69972.
DR RefSeq; NP_390661.2; NC_000964.3.
DR RefSeq; WP_003245996.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; P94446; -.
DR SMR; P94446; -.
DR STRING; 224308.BSU27830; -.
DR PaxDb; P94446; -.
DR PRIDE; P94446; -.
DR EnsemblBacteria; CAB14743; CAB14743; BSU_27830.
DR GeneID; 937516; -.
DR KEGG; bsu:BSU27830; -.
DR PATRIC; fig|224308.179.peg.3024; -.
DR OMA; NTRPIGY; -.
DR BioCyc; BSUB:BSU27830-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0043595; C:endospore cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR InterPro; IPR019076; Spore_lipoprot_YhcN/YlaJ-like.
DR Pfam; PF09580; Spore_YhcN_YlaJ; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal; Sporulation.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 22..198
FT /note="Sporulation cortex protein CoxA"
FT /id="PRO_0000079277"
FT REGION 91..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 107
FT /note="N -> D (in Ref. 2; CAB75323 and 3; CAB14743)"
FT /evidence="ECO:0000305"
FT CONFLICT 137
FT /note="V -> I (in Ref. 1; BAA24944)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 198 AA; 22117 MW; 49A5DB048021F7AD CRC64;
MGKKMTIASL ILMTAGLTAC GANDNAMNDT RNNGNTRPIG YYTNENDADR QGDGIDHDGP
VSELMEDQND GNRNTTNVNN RDRVTADDRV PLATDGTYNN TNNRNMNRNA ANNGYDNQEN
RRLAAKIANR VKQVKNVNDT QVMVSDDRVV IAVKSHREFT KSDRDNVVKA ARNYANGRDV
QVSTDKGLFR KLHKMNNR
