ID   COXM2_CAEEL             Reviewed;         102 AA.
AC   Q8MNU7;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=COX assembly mitochondrial protein 2 homolog;
GN   ORFNames=C35D10.17;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   FUNCTION.
RX   PubMed=20220131; DOI=10.1074/jbc.m110.104786;
RA   Horn D., Zhou W., Trevisson E., Al-Ali H., Harris T.K., Salviati L.,
RA   Barrientos A.;
RT   "The conserved mitochondrial twin Cx9C protein Cmc2 Is a Cmc1 homologue
RT   essential for cytochrome c oxidase biogenesis.";
RL   J. Biol. Chem. 285:15088-15099(2010).
CC   -!- FUNCTION: May be involved in cytochrome c oxidase biogenesis.
CC       {ECO:0000269|PubMed:20220131}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CMC family. {ECO:0000305}.
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DR   EMBL; FO080789; CCD66790.1; -; Genomic_DNA.
DR   RefSeq; NP_741118.1; NM_171105.4.
DR   AlphaFoldDB; Q8MNU7; -.
DR   STRING; 6239.C35D10.17; -.
DR   EPD; Q8MNU7; -.
DR   PaxDb; Q8MNU7; -.
DR   PeptideAtlas; Q8MNU7; -.
DR   EnsemblMetazoa; C35D10.17.1; C35D10.17.1; WBGene00016452.
DR   EnsemblMetazoa; C35D10.17.2; C35D10.17.2; WBGene00016452.
DR   UCSC; C35D10.17; c. elegans.
DR   WormBase; C35D10.17; CE30625; WBGene00016452; -.
DR   eggNOG; KOG4148; Eukaryota.
DR   GeneTree; ENSGT00390000016908; -.
DR   HOGENOM; CLU_179519_0_0_1; -.
DR   InParanoid; Q8MNU7; -.
DR   OMA; HSEKPIG; -.
DR   OrthoDB; 1546992at2759; -.
DR   PhylomeDB; Q8MNU7; -.
DR   PRO; PR:Q8MNU7; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00016452; Expressed in larva and 3 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   InterPro; IPR013892; Cyt_c_biogenesis_Cmc1-like.
DR   PANTHER; PTHR22977; PTHR22977; 1.
DR   Pfam; PF08583; Cmc1; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Mitochondrion; Reference proteome.
FT   CHAIN           1..102
FT                   /note="COX assembly mitochondrial protein 2 homolog"
FT                   /id="PRO_0000192945"
FT   DOMAIN          11..55
FT                   /note="CHCH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           14..24
FT                   /note="Cx9C motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           37..47
FT                   /note="Cx9C motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        14..47
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        24..37
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ   SEQUENCE   102 AA;  11993 MW;  C519494F4098A23D CRC64;
     MLPDLSPHLH TKECNMLIEF LQRCHSEKPI GKMIGKCSYW DEAVWQCTKK ERIWRRDNNP
     AYKRRIVELR SLPEKYWTPA LHKLKEDGVL IGGADQSQGC KI