COXM2_DANRE
ID COXM2_DANRE Reviewed; 78 AA.
AC Q6DHJ6; Q801T8;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=COX assembly mitochondrial protein 2 homolog;
GN Name=cmc2;
GN ORFNames=si:busm1-241h12.4, si:dkey-220e7.3-001, si:dz241h12.4-001;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in cytochrome c oxidase biogenesis.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CMC family. {ECO:0000305}.
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DR EMBL; BX908800; CAK05454.1; -; Genomic_DNA.
DR EMBL; AL592048; CAD87824.1; -; Genomic_DNA.
DR EMBL; BC075976; AAH75976.1; -; mRNA.
DR RefSeq; NP_001002614.1; NM_001002614.2.
DR RefSeq; NP_001269068.1; NM_001282139.1.
DR AlphaFoldDB; Q6DHJ6; -.
DR SMR; Q6DHJ6; -.
DR STRING; 7955.ENSDARP00000118380; -.
DR PaxDb; Q6DHJ6; -.
DR Ensembl; ENSDART00000064076; ENSDARP00000064075; ENSDARG00000043635.
DR Ensembl; ENSDART00000138533; ENSDARP00000118380; ENSDARG00000043635.
DR Ensembl; ENSDART00000191303; ENSDARP00000147638; ENSDARG00000043635.
DR GeneID; 368857; -.
DR KEGG; dre:368857; -.
DR CTD; 56942; -.
DR ZFIN; ZDB-GENE-030616-409; cmc2.
DR eggNOG; KOG4148; Eukaryota.
DR GeneTree; ENSGT00390000016908; -.
DR HOGENOM; CLU_169286_2_0_1; -.
DR InParanoid; Q6DHJ6; -.
DR OMA; HSEKPIG; -.
DR OrthoDB; 1546992at2759; -.
DR PhylomeDB; Q6DHJ6; -.
DR TreeFam; TF314049; -.
DR PRO; PR:Q6DHJ6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 18.
DR Bgee; ENSDARG00000043635; Expressed in heart and 24 other tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR InterPro; IPR013892; Cyt_c_biogenesis_Cmc1-like.
DR PANTHER; PTHR22977; PTHR22977; 1.
DR Pfam; PF08583; Cmc1; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Mitochondrion; Reference proteome.
FT CHAIN 1..78
FT /note="COX assembly mitochondrial protein 2 homolog"
FT /id="PRO_0000365089"
FT DOMAIN 11..55
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT REGION 52..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 14..24
FT /note="Cx9C motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 37..47
FT /note="Cx9C motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 14..47
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 24..37
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 78 AA; 9480 MW; E0F42849A0D4F83C CRC64;
MHPDLSPHLH TDECNQLITL LKQCHKEHNV LKFFGTCNDM DRAMRECLRK EYQTKRERSK
AHAEEMRRRL KEQPKEHP
