COXZ_BRUSU
ID COXZ_BRUSU Reviewed; 201 AA.
AC Q8G261; G0K720;
DT 31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Cytochrome c oxidase assembly protein CtaG {ECO:0000255|HAMAP-Rule:MF_00155};
GN Name=ctaG {ECO:0000255|HAMAP-Rule:MF_00155};
GN OrderedLocusNames=BR0471, BS1330_I0472;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- FUNCTION: Exerts its effect at some terminal stage of cytochrome c
CC oxidase synthesis, probably by being involved in the insertion of the
CC copper B into subunit I. {ECO:0000255|HAMAP-Rule:MF_00155}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00155}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00155}; Periplasmic side {ECO:0000255|HAMAP-
CC Rule:MF_00155}.
CC -!- SIMILARITY: Belongs to the COX11/CtaG family. {ECO:0000255|HAMAP-
CC Rule:MF_00155}.
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DR EMBL; AE014291; AAN29414.1; -; Genomic_DNA.
DR EMBL; CP002997; AEM17827.1; -; Genomic_DNA.
DR RefSeq; WP_004690616.1; NZ_KN046804.1.
DR AlphaFoldDB; Q8G261; -.
DR SMR; Q8G261; -.
DR EnsemblBacteria; AEM17827; AEM17827; BS1330_I0472.
DR GeneID; 45051581; -.
DR GeneID; 55590227; -.
DR KEGG; bms:BR0471; -.
DR KEGG; bsi:BS1330_I0472; -.
DR PATRIC; fig|204722.21.peg.1430; -.
DR HOGENOM; CLU_045000_5_0_5; -.
DR OMA; NKLECFC; -.
DR PhylomeDB; Q8G261; -.
DR Proteomes; UP000007104; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0008535; P:respiratory chain complex IV assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.370.10; -; 1.
DR HAMAP; MF_00155; CtaG; 1.
DR InterPro; IPR023471; CtaG/Cox11_dom_sf.
DR InterPro; IPR007533; Cyt_c_oxidase_assmbl_CtaG.
DR Pfam; PF04442; CtaG_Cox11; 1.
DR PIRSF; PIRSF005413; COX11; 1.
DR SUPFAM; SSF110111; SSF110111; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Copper; Membrane; Signal-anchor;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..201
FT /note="Cytochrome c oxidase assembly protein CtaG"
FT /id="PRO_0000206034"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00155"
FT TRANSMEM 13..35
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00155"
FT TOPO_DOM 36..201
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00155"
SQ SEQUENCE 201 AA; 22472 MW; 64ED1CCF119944A6 CRC64;
MTDQGENEKK QRRSNATIAV ACLSFFVCMI GAAYASVPLY RIFCQVTGYG GTTQRVEQYS
DTILDKTIKV RFDANIANGL PWDFKPMQRE VTVRIGETTM IKYEAHNLFG EETYGRASFN
VAPGRAGAYF NKVECFCFTD NTLKPGEDLE LPVVFFVDPE FVNDPDLKDV KTITLSYTFF
PIDKPRPVVN AKAVGSTRNG G