ID   CP090_HUMAN             Reviewed;         182 AA.
AC   A8MZG2;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   28-FEB-2018, sequence version 3.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Uncharacterized protein C16orf90;
GN   Name=C16orf90;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-147.
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC004224; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DR731281; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS45397.1; -.
DR   RefSeq; NP_001073993.1; NM_001080524.1.
DR   AlphaFoldDB; A8MZG2; -.
DR   BioGRID; 571081; 2.
DR   STRING; 9606.ENSP00000401335; -.
DR   BioMuta; C16orf90; -.
DR   PRIDE; A8MZG2; -.
DR   Antibodypedia; 71412; 11 antibodies from 6 providers.
DR   DNASU; 646174; -.
DR   Ensembl; ENST00000437192.8; ENSP00000401335.3; ENSG00000215131.11.
DR   GeneID; 646174; -.
DR   KEGG; hsa:646174; -.
DR   MANE-Select; ENST00000437192.8; ENSP00000401335.3; NM_001080524.2; NP_001073993.1.
DR   UCSC; uc002cvi.4; human.
DR   CTD; 646174; -.
DR   GeneCards; C16orf90; -.
DR   HGNC; HGNC:34455; C16orf90.
DR   HPA; ENSG00000215131; Tissue enriched (testis).
DR   neXtProt; NX_A8MZG2; -.
DR   VEuPathDB; HostDB:ENSG00000215131; -.
DR   eggNOG; ENOG502SU94; Eukaryota.
DR   GeneTree; ENSGT00390000014875; -.
DR   HOGENOM; CLU_125529_0_0_1; -.
DR   InParanoid; A8MZG2; -.
DR   OMA; FRPKRSW; -.
DR   OrthoDB; 1286663at2759; -.
DR   PhylomeDB; A8MZG2; -.
DR   TreeFam; TF337958; -.
DR   PathwayCommons; A8MZG2; -.
DR   SignaLink; A8MZG2; -.
DR   BioGRID-ORCS; 646174; 20 hits in 1031 CRISPR screens.
DR   ChiTaRS; C16orf90; human.
DR   GenomeRNAi; 646174; -.
DR   Pharos; A8MZG2; Tdark.
DR   PRO; PR:A8MZG2; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   RNAct; A8MZG2; protein.
DR   Bgee; ENSG00000215131; Expressed in left testis and 17 other tissues.
DR   ExpressionAtlas; A8MZG2; baseline and differential.
DR   InterPro; IPR027978; DUF4644.
DR   PANTHER; PTHR37334; PTHR37334; 1.
DR   Pfam; PF15486; DUF4644; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..182
FT                   /note="Uncharacterized protein C16orf90"
FT                   /id="PRO_0000343581"
FT   REGION          17..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          128..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        29
FT                   /note="D -> V (in Ref. 2; DR731281)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        133
FT                   /note="S -> R (in Ref. 2; DR731281)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   182 AA;  19564 MW;  8C98480CC4616641 CRC64;
     MEALVCAFSE LHIREDAVSQ AQGRPGHPDA PPNIYEGGLG SPQPQCPSAQ GSKPKNFRLR
     HLRGLGLYLE SHPPPTGQCE SHWLGRLMAG GCLPQPEGTA WALDLPQGTL GPRNSLCSAL
     LEARLPRDSL GSSASSSSMD PDKGALPQPS PSRLRPKRSW GTWEEAMCPL CKRTRSGALE
     RP