CP090_MOUSE
ID CP090_MOUSE Reviewed; 171 AA.
AC Q8BT88; B9EJK2; Q9D9P5;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 2.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Uncharacterized protein C16orf90 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8BT88-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8BT88-2; Sequence=VSP_034617, VSP_034618, VSP_034619;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC25379.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK006619; BAB24677.1; -; mRNA.
DR EMBL; AK012792; BAC25379.1; ALT_FRAME; mRNA.
DR EMBL; BC147295; AAI47296.1; -; mRNA.
DR CCDS; CCDS49746.1; -. [Q8BT88-1]
DR RefSeq; NP_082760.2; NM_028484.2. [Q8BT88-1]
DR AlphaFoldDB; Q8BT88; -.
DR PaxDb; Q8BT88; -.
DR PRIDE; Q8BT88; -.
DR Antibodypedia; 71412; 11 antibodies from 6 providers.
DR Ensembl; ENSMUST00000115859; ENSMUSP00000111525; ENSMUSG00000005983. [Q8BT88-1]
DR GeneID; 73261; -.
DR KEGG; mmu:73261; -.
DR UCSC; uc007xyz.1; mouse. [Q8BT88-1]
DR MGI; MGI:1920511; 1700037C18Rik.
DR VEuPathDB; HostDB:ENSMUSG00000005983; -.
DR eggNOG; ENOG502SU94; Eukaryota.
DR GeneTree; ENSGT00390000014875; -.
DR InParanoid; Q8BT88; -.
DR OMA; FRPKRSW; -.
DR OrthoDB; 1286663at2759; -.
DR PhylomeDB; Q8BT88; -.
DR TreeFam; TF337958; -.
DR BioGRID-ORCS; 73261; 4 hits in 71 CRISPR screens.
DR PRO; PR:Q8BT88; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q8BT88; protein.
DR Bgee; ENSMUSG00000005983; Expressed in spermatid and 212 other tissues.
DR ExpressionAtlas; Q8BT88; baseline and differential.
DR Genevisible; Q8BT88; MM.
DR InterPro; IPR027978; DUF4644.
DR PANTHER; PTHR37334; PTHR37334; 1.
DR Pfam; PF15486; DUF4644; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..171
FT /note="Uncharacterized protein C16orf90 homolog"
FT /id="PRO_0000343582"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1
FT /note="M -> MEALVCAFSELRIRE (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034617"
FT VAR_SEQ 121..127
FT /note="SSSSMDP -> TIIPTMA (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034618"
FT VAR_SEQ 128..171
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034619"
SQ SEQUENCE 171 AA; 18157 MW; F108A65A6F0D8996 CRC64;
MDAVSWAPGR PSHPDTPPNI YEGGLGAQQQ QGPSAQGSKP KNFRLRHLRS LALYLPGHMQ
PAGQCGSHWL GRLMAGGSLT RPEGSPWPLD LPQGTLGPGN SHCSALLEAH LPRDSLGNTA
SSSSMDPAKG VPSQSGPPEG LGLRPKRSWR ALEETMCPLC KRTRSGALER T