CP096_HUMAN
ID CP096_HUMAN Reviewed; 1141 AA.
AC A6NNT2; C9JH24;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 3.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Uncharacterized protein C16orf96 {ECO:0000305};
GN Name=C16orf96 {ECO:0000312|HGNC:HGNC:40031};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
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DR EMBL; AC023830; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS53986.1; -.
DR RefSeq; NP_001138483.1; NM_001145011.1.
DR RefSeq; XP_011520777.1; XM_011522475.2.
DR AlphaFoldDB; A6NNT2; -.
DR SMR; A6NNT2; -.
DR BioGRID; 131169; 5.
DR IntAct; A6NNT2; 1.
DR STRING; 9606.ENSP00000415027; -.
DR iPTMnet; A6NNT2; -.
DR PhosphoSitePlus; A6NNT2; -.
DR BioMuta; C16orf96; -.
DR MassIVE; A6NNT2; -.
DR PaxDb; A6NNT2; -.
DR PeptideAtlas; A6NNT2; -.
DR PRIDE; A6NNT2; -.
DR ProteomicsDB; 1635; -.
DR Antibodypedia; 51179; 8 antibodies from 4 providers.
DR DNASU; 342346; -.
DR Ensembl; ENST00000444310.5; ENSP00000415027.3; ENSG00000205832.8.
DR GeneID; 342346; -.
DR KEGG; hsa:342346; -.
DR MANE-Select; ENST00000444310.5; ENSP00000415027.3; NM_001145011.2; NP_001138483.1.
DR UCSC; uc010uxn.3; human.
DR CTD; 342346; -.
DR DisGeNET; 342346; -.
DR GeneCards; C16orf96; -.
DR HGNC; HGNC:40031; C16orf96.
DR HPA; ENSG00000205832; Tissue enriched (testis).
DR neXtProt; NX_A6NNT2; -.
DR OpenTargets; ENSG00000205832; -.
DR VEuPathDB; HostDB:ENSG00000205832; -.
DR eggNOG; ENOG502RC3N; Eukaryota.
DR GeneTree; ENSGT00940000162979; -.
DR HOGENOM; CLU_283220_0_0_1; -.
DR InParanoid; A6NNT2; -.
DR OMA; VNTKLVH; -.
DR OrthoDB; 430976at2759; -.
DR PhylomeDB; A6NNT2; -.
DR TreeFam; TF339506; -.
DR PathwayCommons; A6NNT2; -.
DR SignaLink; A6NNT2; -.
DR BioGRID-ORCS; 342346; 14 hits in 1040 CRISPR screens.
DR ChiTaRS; C16orf96; human.
DR GenomeRNAi; 342346; -.
DR Pharos; A6NNT2; Tdark.
DR PRO; PR:A6NNT2; -.
DR Proteomes; UP000005640; Chromosome 16.
DR RNAct; A6NNT2; protein.
DR Bgee; ENSG00000205832; Expressed in left testis and 41 other tissues.
DR InterPro; IPR032013; DUF4795.
DR Pfam; PF16043; DUF4795; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1141
FT /note="Uncharacterized protein C16orf96"
FT /id="PRO_0000345628"
FT REGION 296..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1105..1141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 74..101
FT /evidence="ECO:0000255"
FT COILED 145..176
FT /evidence="ECO:0000255"
FT COILED 757..810
FT /evidence="ECO:0000255"
FT COMPBIAS 463..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1141 AA; 125041 MW; 2EC01FC5481CC306 CRC64;
MSFSLTFTEL ANIAIPQCGV LNFKALHLLL HGILEHIHMA ELKKVLSGDE DFLQTSQVVI
MPREGDAQPI LNPMKRLSNV FDHVVSRLDK LENQLALLQD LPSTAQLLEA SQGTARPVQD
LWHLIKLRKM VEGHDEVMAK SMQTLQDLLT DLHALQVTIT ALRKEVDMLK NMLDKVHPER
MDIFAEDFKI QNWKMVALQR EVASLQNKFK TIPKTEDMVL WSGLHDAMFT SEIGSSPLDL
WQSVEQLPEA ALAQTTKYLE ATRAIQVSEP VQNPQLLQTV WHYEVPELLP EGSSAQAVSL
SRAQEPAQPP ALTPESAPGC TTEFAPGPAP GTEPVPGLEL GLELEPVPAL GPVPGPSVTP
GSLPAPWPVL GPVPAPGAQP PPLGDWPALP RRWPLPQGWP RVGSWPLWDL GVLRPTQPQP
SRAPPPATEF GSLWPRPLQP YQSRQGEALQ LAAVQVKGEE NDVPSLRGLR ERARKDGAPK
DRTRKDGVPK DRGGKDVDPK DRAHKDDVPK DRGGKDVDPK DRAHKDDVPK DRGGKDGDPK
DRVGKDGAPK EAQPKAPQSA LHRLKTTAAI AAAAAAAYAA ATSSAAQAAK VAAKFVKDAP
ATKMAAIATD TAAAGPLGVF ADVLGAGPSR GATESQILGD DSEIYEILSP SYSAASIGPD
PALSQAMVAT KQAMSPEDKK RAVKYSMSHI AQIPVKHDSL KEEFAQLSCN LNQRLSYLAN
MGGPSSLGTT VDILQKKIGS LQKSRLKEEE LERIWGNQIE MMKDRYITLD KAVENLQIRM
DEFKTLQAQI KRLEMNKVNK STMEEELREK ADRSALAGKA SRVDLETVAL ELNEMIQGIL
FKVTIHEDSW KKAMEELSKD VNTKLVHSDL DPLKKEMEEV WKIVRKLLIE GLRLDPDSAA
GFRRKLFKRV KCISCDRPVE MMTGPQLITI RKAHLLSRLR PASANSCEYL QRQQMREQQW
LQLQDLGIQE DCQQDWGDGP QNATSLKCKS CNLLTLYPYG DPHVIDYDSA EVDILGVDGI
LYKGRVNSQR GAQPLAVAKE LAAVKAPSPP SQSLYDRVHS SALFGAICPP LCPRSSACSA
ASGPHLTMPA RPPSLPPLLL LPPLIPSLRD PQQAPGSTRL SRAPHIESRV GRKPPEEPAN
P
