CP096_MOUSE
ID CP096_MOUSE Reviewed; 1145 AA.
AC E9QMW4; Q3V087;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 1.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=Uncharacterized protein C16orf96 homolog {ECO:0000305};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=E9QMW4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=E9QMW4-2; Sequence=VSP_042127;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAE21617.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC167018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK133365; BAE21617.1; ALT_FRAME; mRNA.
DR RefSeq; NP_084468.1; NM_030192.1. [E9QMW4-1]
DR AlphaFoldDB; E9QMW4; -.
DR STRING; 10090.ENSMUSP00000097784; -.
DR iPTMnet; E9QMW4; -.
DR PhosphoSitePlus; E9QMW4; -.
DR MaxQB; E9QMW4; -.
DR PaxDb; E9QMW4; -.
DR PRIDE; E9QMW4; -.
DR Antibodypedia; 51179; 8 antibodies from 4 providers.
DR Ensembl; ENSMUST00000100211; ENSMUSP00000097784; ENSMUSG00000022518. [E9QMW4-1]
DR GeneID; 78809; -.
DR KEGG; mmu:78809; -.
DR UCSC; uc007yam.1; mouse. [E9QMW4-2]
DR UCSC; uc012aav.1; mouse. [E9QMW4-1]
DR MGI; MGI:1926059; 4930562C15Rik.
DR VEuPathDB; HostDB:ENSMUSG00000022518; -.
DR eggNOG; ENOG502RC3N; Eukaryota.
DR GeneTree; ENSGT00940000162979; -.
DR HOGENOM; CLU_283220_0_0_1; -.
DR InParanoid; E9QMW4; -.
DR OMA; VNTKLVH; -.
DR OrthoDB; 430976at2759; -.
DR TreeFam; TF339506; -.
DR BioGRID-ORCS; 78809; 2 hits in 33 CRISPR screens.
DR PRO; PR:E9QMW4; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; E9QMW4; protein.
DR Bgee; ENSMUSG00000022518; Expressed in animal zygote and 48 other tissues.
DR ExpressionAtlas; E9QMW4; baseline and differential.
DR Genevisible; E9QMW4; MM.
DR InterPro; IPR032013; DUF4795.
DR Pfam; PF16043; DUF4795; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..1145
FT /note="Uncharacterized protein C16orf96 homolog"
FT /id="PRO_0000413539"
FT REGION 489..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1100..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 74..101
FT /evidence="ECO:0000255"
FT COILED 186..212
FT /evidence="ECO:0000255"
FT COILED 744..816
FT /evidence="ECO:0000255"
FT COMPBIAS 500..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 800..1145
FT /note="ILKAEIERLDLVKADKNVMDLELNEKANRDALASKANRVDLETVAMELNEMI
FT HSMLLKITNYESDWKKALKHLRKDLNTKLVQSDLNSLKKDIEEVWKVVRKLLLEGLRFD
FT PDSAAGFKKKLFERVKCISCDRPVEMMTGPQLITIRNTHGLSRIRPASANSYEYLQRQL
FT IREQQQHLHFQNFGVHEEGQGFQKDWGDGPRNENTLKHKSHDLSTLYPYGDPELMNYDT
FT AEVDILGVDGVLYKGRMSSQFGTRTGEKDIAAVKVSYYTIPNLTDRVRPGSLLAPGYPP
FT LSPRTSITSATTLHSATNTTTARPPSLPPVPQLPPLIPVSRDTQEAPGSAKRLKSPRL
FT -> VRRSEDQEGGTGELLLGTTRPSSKGLQNTGELDNILFCINYTSIKNKSQGLER
FT (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_042127"
SQ SEQUENCE 1145 AA; 127660 MW; 3422DB0A6B3B210B CRC64;
MSFSITFTEL VNVAIPQCGV VNFKALHLLL QGILEHIQIT ELKKVLSGEE DFLQSSPAVF
IPREGDAQPV INPMKRLSNI FDQVVDRIEK IESKLAEMQD IPTTSQLVEE SYGDKRPAEE
MWNNIKIQKR IEGNEKATEK FTRTLQDLLN DLHVLKGSVE TVQKDVDTIK FIFEKVNPQK
LELLGDDLKT QSRKLGALQR EVVTLQNKVR AVPQPEEMVL WSGLHEAMFS PEQQKLEVEP
SGVWQSMVSL PGSPLEQPED AGYIHIPIHS ATPVPTMVQL GTTGALREEE LTRAVELADS
QRPELAQAFV SQTQRLERAQ ASVSQTQRLE RAQASVSQTQ RLERAQASVS QTQNLRQTAP
FPFPVPGFVP GPDFMPVYGP RPGMATPSAW ALPRGLARGN YWPIWGIGPY QPGQGPLQPM
GPMPRVPFPA MGSDIPWTQP LPQGTQWYPN IEERGPEYEE QYPEGYQEEM PMDEAPQEEM
AVYGALEEEI PTEGAPQDGI PKGRARERIS KEKVPKYRTP KERVSYHKAS KDVSPEDTGT
KDEAPEVKVL KKVVYKDRPQ KDKAPEPRRK GPSSAIKKLR SAIASAAAAA AAYAAHANSA
AQLAKDAVKA IQDVPANQLA AKAALIASSG PLGAFADFLG AGFGHGATSN TPFDEGELEE
FPEEFAAPFN PFTSKPVLSQ AMISATQATS PEEKKKAVQY SMGHIAQMPS RHNSLKEEFT
NLSTTLNQRL NYLANMGSSG VLGSTVNVLE EKIINLQKAR LQEEELERVW GHQIDTMKSH
YMVLDRAVER LQIRMDDLKI LKAEIERLDL VKADKNVMDL ELNEKANRDA LASKANRVDL
ETVAMELNEM IHSMLLKITN YESDWKKALK HLRKDLNTKL VQSDLNSLKK DIEEVWKVVR
KLLLEGLRFD PDSAAGFKKK LFERVKCISC DRPVEMMTGP QLITIRNTHG LSRIRPASAN
SYEYLQRQLI REQQQHLHFQ NFGVHEEGQG FQKDWGDGPR NENTLKHKSH DLSTLYPYGD
PELMNYDTAE VDILGVDGVL YKGRMSSQFG TRTGEKDIAA VKVSYYTIPN LTDRVRPGSL
LAPGYPPLSP RTSITSATTL HSATNTTTAR PPSLPPVPQL PPLIPVSRDT QEAPGSAKRL
KSPRL
