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CPB1_CAEJA
ID   CPB1_CAEJA              Reviewed;         617 AA.
AC   Q6E3C7;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 1;
GN   Name=cpb-1;
OS   Caenorhabditis japonica.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=281687;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=15231741; DOI=10.1101/gr.2639304;
RA   Cho S., Jin S.W., Cohen A., Ellis R.E.;
RT   "A phylogeny of Caenorhabditis reveals frequent loss of introns during
RT   nematode evolution.";
RL   Genome Res. 14:1207-1220(2004).
CC   -!- FUNCTION: Cytoplasmic polyadenylation element binding protein that
CC       binds to and regulates the translation of specific mRNAs. Essential for
CC       progression through meiosis. Involved in spermatogenesis (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with fbf-1. {ECO:0000250}.
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DR   EMBL; AY589645; AAT72429.1; -; Genomic_DNA.
DR   EMBL; AY589595; AAT72412.1; -; mRNA.
DR   AlphaFoldDB; Q6E3C7; -.
DR   SMR; Q6E3C7; -.
DR   STRING; 281687.CJA18184; -.
DR   eggNOG; KOG0129; Eukaryota.
DR   HOGENOM; CLU_035644_0_0_1; -.
DR   InParanoid; Q6E3C7; -.
DR   OMA; KHNYAPY; -.
DR   Proteomes; UP000005237; Unassembled WGS sequence.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 4.10.640.40; -; 1.
DR   InterPro; IPR032296; CEBP_ZZ.
DR   InterPro; IPR038446; CEBP_ZZ_sf.
DR   InterPro; IPR034819; CPEB.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR12566; PTHR12566; 1.
DR   Pfam; PF16366; CEBP_ZZ; 1.
DR   Pfam; PF16367; RRM_7; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Reference proteome; Repeat;
KW   RNA-binding; Spermatogenesis.
FT   CHAIN           1..617
FT                   /note="Cytoplasmic polyadenylation element-binding protein
FT                   1"
FT                   /id="PRO_0000081510"
FT   DOMAIN          273..377
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          394..465
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..568
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        544..560
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        592..608
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  67879 MW;  F9FF95B1713C6614 CRC64;
     MQSQLKACGD APAPSCSLHH RRTISKKPSN GGNSGGGGGG VNSAYLATDV TTLDINAMFQ
     SKKMKRHGAG VTAPSTPANY LGASAGAGQA NPAHFNFPSY LNPASFYPNV DLLGGSSEHL
     PPLMSVPAYK PTSMLHGFSD AASAMDFAQL TEELNALQNL SASFPNSTPN AFQSLFATDS
     PSSFLTSSAV SSHLAKPSPL TANSVRGAGG RKNRMVEVKM INERPVVIVS DPQAASASAR
     SQIVHLNRNV LGVLKGLEAS KKRSISAEPL YSRKVFIGGL PIDVTEEEVW ATFGWFGKVL
     VDWPRRPEHG GRGDFYEMDM GRRNSRSVSG YVFLVFQDEK AVQELVNACE LYENKYYLQL
     SSPTMADKAV QVRAWRLSDI DYFCDENASV DHRRTVFIGG VPRPTRASDL AYCLQQHYGK
     VSYVGIDIDP ELKYPKGAAR VTFATAQSFV RAISGRFVQV THADTNKRVE IKPYVMEDQH
     CDECQGKLCK HNYAPYFCGD SSCLQYYCEA CWDRMHYAMC DNRADHRPMV RTGDQTRILP
     RPPHHSTSHY HHRSTPSHHH NHTHQNVTSS LLEHAPHLQN TSIISRIVNR NNQNNNSANS
     TPPQMKQFSA IPTAIGY
 
 
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