ID   CPCTL_NOSS1             Reviewed;         198 AA.
AC   Q8YZ40;
DT   11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Phycocyanobilin lyase CpcT homolog;
GN   Name=cpcT2; Synonyms=cpeT2; OrderedLocusNames=alr0647;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
RN   [2]
RP   INDUCTION, FUNCTION, AND LACK OF CHROMOPHORE LYASE ACTIVITY IN VITRO.
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=17895251; DOI=10.1074/jbc.m703038200;
RA   Zhao K.H., Zhang J., Tu J.M., Bohm S., Ploscher M., Eichacker L.,
RA   Bubenzer C., Scheer H., Wang X., Zhou M.;
RT   "Lyase activities of CpcS- and CpcT-like proteins from Nostoc PCC7120 and
RT   sequential reconstitution of binding sites of phycoerythrocyanin and
RT   phycocyanin beta-subunits.";
RL   J. Biol. Chem. 282:34093-34103(2007).
RN   [3]
RP   FUNCTION, AND LACK OF CHROMOPHORE LYASE ACTIVITY IN VITRO.
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=17726096; DOI=10.1073/pnas.0706209104;
RA   Zhao K.H., Su P., Tu J.M., Wang X., Liu H., Ploscher M., Eichacker L.,
RA   Yang B., Zhou M., Scheer H.;
RT   "Phycobilin:cystein-84 biliprotein lyase, a near-universal lyase for
RT   cysteine-84-binding sites in cyanobacterial phycobiliproteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:14300-14305(2007).
CC   -!- FUNCTION: Covalently attaches a chromophore to Cys residue(s) of
CC       phycobiliproteins (By similarity). In vitro is not seen to act as a
CC       chromophore lyase for ApcA1, ApcA2, ApcB, ApcD, ApcF, CpcB or PecB, the
CC       lyase activity is therefore unsure. {ECO:0000250,
CC       ECO:0000269|PubMed:17726096, ECO:0000269|PubMed:17895251}.
CC   -!- INDUCTION: Induced by nitrogen starvation.
CC       {ECO:0000269|PubMed:17895251}.
CC   -!- SIMILARITY: Belongs to the CpcT/CpeT biliprotein lyase family.
CC       {ECO:0000305}.
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DR   EMBL; BA000019; BAB72605.1; -; Genomic_DNA.
DR   PIR; AF1887; AF1887.
DR   RefSeq; WP_010994823.1; NZ_RSCN01000009.1.
DR   AlphaFoldDB; Q8YZ40; -.
DR   SMR; Q8YZ40; -.
DR   STRING; 103690.17129993; -.
DR   EnsemblBacteria; BAB72605; BAB72605; BAB72605.
DR   KEGG; ana:alr0647; -.
DR   eggNOG; ENOG502ZC00; Bacteria.
DR   OMA; VHLRLWQ; -.
DR   OrthoDB; 1217830at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017009; P:protein-phycocyanobilin linkage; IEA:InterPro.
DR   CDD; cd16338; CpcT; 1.
DR   Gene3D; 2.40.128.590; -; 1.
DR   HAMAP; MF_01460; Chrphore_lyase_CpxT; 1.
DR   InterPro; IPR010404; CpcT/CpeT.
DR   InterPro; IPR038672; CpcT/CpeT_sf.
DR   PANTHER; PTHR35137; PTHR35137; 1.
DR   Pfam; PF06206; CpeT; 1.
PE   2: Evidence at transcript level;
KW   Lyase; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Phycocyanobilin lyase CpcT homolog"
FT                   /id="PRO_0000403161"
SQ   SEQUENCE   198 AA;  22396 MW;  3E84D7AB9BAF5F54 CRC64;
     MSFSPQLVNL GNYLAGEFDN REQALGEPIW FVHLRLWQRP VDLFSDDSIT LFAEQANIVN
     LDRPYRQRIL RLMPAPDSET GLYVQYYMPK NPSALIGAGR HPDLLKTLTP QQLELLPGCV
     LSVSQQTVAP NSYQFTASPL PNTCCTFSYL ENTVQVSLGF AVTETELHTY DKGIDQETGK
     ATWGAIVGPY RYTKREQY