CPG8_CAEEL
ID CPG8_CAEEL Reviewed; 115 AA.
AC Q21175; Q86NG7;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2001, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Chondroitin proteoglycan 8;
DE Flags: Precursor;
GN Name=cpg-8 {ECO:0000312|WormBase:K03B4.7a}; ORFNames=K03B4.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1] {ECO:0000305, ECO:0000312|EMBL:ABC65818.1}
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), IDENTIFICATION BY MASS
RP SPECTROMETRY, AND GLYCOSYLATION AT SER-61; SER-63; SER-84; SER-88 AND
RP SER-109.
RX PubMed=16785326; DOI=10.1083/jcb.200603003;
RA Olson S.K., Bishop J.R., Yates J.R., Oegema K., Esko J.D.;
RT "Identification of novel chondroitin proteoglycans in Caenorhabditis
RT elegans: embryonic cell division depends on CPG-1 and CPG-2.";
RL J. Cell Biol. 173:985-994(2006).
RN [2] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a {ECO:0000269|PubMed:16785326};
CC IsoId=Q21175-1; Sequence=Displayed;
CC Name=b {ECO:0000269|PubMed:9851916};
CC IsoId=Q21175-2; Sequence=VSP_052686;
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DR EMBL; DQ340630; ABC65818.1; -; mRNA.
DR EMBL; FO081359; CCD71030.1; -; Genomic_DNA.
DR EMBL; FO081359; CCD71031.1; -; Genomic_DNA.
DR PIR; T29728; T29728.
DR RefSeq; NP_504264.1; NM_071863.6. [Q21175-1]
DR RefSeq; NP_872155.1; NM_182355.3. [Q21175-2]
DR AlphaFoldDB; Q21175; -.
DR SMR; Q21175; -.
DR BioGRID; 43912; 2.
DR IntAct; Q21175; 1.
DR STRING; 6239.K03B4.7a; -.
DR iPTMnet; Q21175; -.
DR EPD; Q21175; -.
DR PaxDb; Q21175; -.
DR PeptideAtlas; Q21175; -.
DR EnsemblMetazoa; K03B4.7a.1; K03B4.7a.1; WBGene00019357. [Q21175-1]
DR EnsemblMetazoa; K03B4.7b.1; K03B4.7b.1; WBGene00019357. [Q21175-2]
DR GeneID; 178860; -.
DR KEGG; cel:CELE_K03B4.7; -.
DR UCSC; K03B4.7a.1; c. elegans. [Q21175-1]
DR CTD; 178860; -.
DR WormBase; K03B4.7a; CE28581; WBGene00019357; cpg-8. [Q21175-1]
DR WormBase; K03B4.7b; CE33133; WBGene00019357; cpg-8. [Q21175-2]
DR eggNOG; ENOG502R8AK; Eukaryota.
DR HOGENOM; CLU_2199364_0_0_1; -.
DR InParanoid; Q21175; -.
DR OMA; YSVHKTE; -.
DR OrthoDB; 1626663at2759; -.
DR PRO; PR:Q21175; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00019357; Expressed in embryo and 4 other tissues.
PE 1: Evidence at protein level;
KW Alternative splicing; Glycoprotein; Proteoglycan; Reference proteome;
KW Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..115
FT /note="Chondroitin proteoglycan 8"
FT /id="PRO_0000320228"
FT REGION 33..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 61
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT CARBOHYD 63
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT CARBOHYD 84
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT CARBOHYD 88
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT CARBOHYD 109
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT VAR_SEQ 59..115
FT /note="DGSGSGESPAEEQLRRVVRDVDEEASGEGSGAAEVTSVPVRFVRSVDAEGSG
FT SGSDE -> VSFGLSGSQAWPIFQFFSFALKTKKKSKFFRRSGYELRPRP (in
FT isoform b)"
FT /evidence="ECO:0000303|PubMed:9851916"
FT /id="VSP_052686"
SQ SEQUENCE 115 AA; 12205 MW; 0BADB3627D19DC85 CRC64;
MRPFILLALL VSVTVAFNIF RDEVVPEEQL LAVRRTTRDA SDSSSDSDEK DDAKTTVTDG
SGSGESPAEE QLRRVVRDVD EEASGEGSGA AEVTSVPVRF VRSVDAEGSG SGSDE
