CPLX4_HUMAN
ID CPLX4_HUMAN Reviewed; 160 AA.
AC Q7Z7G2; F1T0L6;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Complexin-4;
DE AltName: Full=Complexin IV;
DE Short=CPX IV;
DE Flags: Precursor;
GN Name=CPLX4;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Brain;
RX PubMed=15911881; DOI=10.1083/jcb.200502115;
RA Reim K., Wegmeyer H., Brandstaetter J.H., Xue M., Rosenmund C.,
RA Dresbach T., Hofmann K., Brose N.;
RT "Structurally and functionally unique complexins at retinal ribbon
RT synapses.";
RL J. Cell Biol. 169:669-680(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Cerebellum;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Retina;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Retina;
RX PubMed=21697133; DOI=10.1167/iovs.11-7479;
RA Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S.,
RA Usami R., Ohtoko K., Kato S.;
RT "Full-length transcriptome analysis of human retina-derived cell lines
RT ARPE-19 and Y79 using the vector-capping method.";
RL Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Complexin that regulates SNARE protein complex-mediated
CC synaptic vesicle fusion (By similarity). Required for the maintenance
CC of synaptic ultrastructure in the adult retina (By similarity).
CC Positively regulates synaptic transmission through synaptic vesicle
CC availability and exocytosis of neurotransmitters at photoreceptor
CC ribbon synapses in the retina (By similarity). Suppresses tonic
CC photoreceptor activity and baseline 'noise' by suppression of Ca(2+)
CC vesicle tonic release and the facilitation of evoked synchronous and
CC asynchronous Ca(2+) vesicle release (By similarity).
CC {ECO:0000250|UniProtKB:Q80WM3}.
CC -!- SUBUNIT: Weakly binds to the SNARE core complex containing SNAP25,
CC VAMP2 and STX1A. {ECO:0000250|UniProtKB:Q80WM3}.
CC -!- INTERACTION:
CC Q7Z7G2; Q15848: ADIPOQ; NbExp=3; IntAct=EBI-18013275, EBI-10827839;
CC Q7Z7G2; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-18013275, EBI-11522760;
CC Q7Z7G2; Q9NVV5-2: AIG1; NbExp=3; IntAct=EBI-18013275, EBI-11957045;
CC Q7Z7G2; Q16853: AOC3; NbExp=3; IntAct=EBI-18013275, EBI-3921628;
CC Q7Z7G2; P05090: APOD; NbExp=3; IntAct=EBI-18013275, EBI-715495;
CC Q7Z7G2; P29972: AQP1; NbExp=3; IntAct=EBI-18013275, EBI-745213;
CC Q7Z7G2; O43315: AQP9; NbExp=3; IntAct=EBI-18013275, EBI-17444777;
CC Q7Z7G2; P07306: ASGR1; NbExp=3; IntAct=EBI-18013275, EBI-1172335;
CC Q7Z7G2; P27449: ATP6V0C; NbExp=3; IntAct=EBI-18013275, EBI-721179;
CC Q7Z7G2; Q12982: BNIP2; NbExp=3; IntAct=EBI-18013275, EBI-752094;
CC Q7Z7G2; P01031: C5; NbExp=3; IntAct=EBI-18013275, EBI-8558308;
CC Q7Z7G2; Q06432: CACNG1; NbExp=3; IntAct=EBI-18013275, EBI-9686780;
CC Q7Z7G2; Q8NHW4: CCL4L2; NbExp=3; IntAct=EBI-18013275, EBI-10271156;
CC Q7Z7G2; P60033: CD81; NbExp=3; IntAct=EBI-18013275, EBI-712921;
CC Q7Z7G2; O14735: CDIPT; NbExp=3; IntAct=EBI-18013275, EBI-358858;
CC Q7Z7G2; O95674: CDS2; NbExp=3; IntAct=EBI-18013275, EBI-3913685;
CC Q7Z7G2; Q8NHS1: CLDND2; NbExp=3; IntAct=EBI-18013275, EBI-11959453;
CC Q7Z7G2; Q6UXB4: CLEC4G; NbExp=3; IntAct=EBI-18013275, EBI-2114729;
CC Q7Z7G2; Q9NWW5: CLN6; NbExp=3; IntAct=EBI-18013275, EBI-6165897;
CC Q7Z7G2; Q96DZ9-2: CMTM5; NbExp=3; IntAct=EBI-18013275, EBI-11522780;
CC Q7Z7G2; O95406: CNIH1; NbExp=3; IntAct=EBI-18013275, EBI-12172273;
CC Q7Z7G2; Q4LDR2: CTXN3; NbExp=3; IntAct=EBI-18013275, EBI-12019274;
CC Q7Z7G2; O43169: CYB5B; NbExp=3; IntAct=EBI-18013275, EBI-1058710;
CC Q7Z7G2; Q9BQA9: CYBC1; NbExp=3; IntAct=EBI-18013275, EBI-2680384;
CC Q7Z7G2; P78329: CYP4F2; NbExp=3; IntAct=EBI-18013275, EBI-1752413;
CC Q7Z7G2; Q9H1M4: DEFB127; NbExp=3; IntAct=EBI-18013275, EBI-10305240;
CC Q7Z7G2; P50402: EMD; NbExp=3; IntAct=EBI-18013275, EBI-489887;
CC Q7Z7G2; Q05329: GAD2; NbExp=3; IntAct=EBI-18013275, EBI-9304251;
CC Q7Z7G2; Q8WWP7: GIMAP1; NbExp=3; IntAct=EBI-18013275, EBI-11991950;
CC Q7Z7G2; Q14416: GRM2; NbExp=3; IntAct=EBI-18013275, EBI-10232876;
CC Q7Z7G2; B0YJ81: HACD1; NbExp=3; IntAct=EBI-18013275, EBI-12051643;
CC Q7Z7G2; Q9HCP6: HHATL; NbExp=3; IntAct=EBI-18013275, EBI-5916693;
CC Q7Z7G2; P09601: HMOX1; NbExp=3; IntAct=EBI-18013275, EBI-2806151;
CC Q7Z7G2; Q9Y5U4: INSIG2; NbExp=3; IntAct=EBI-18013275, EBI-8503746;
CC Q7Z7G2; Q9UBY5: LPAR3; NbExp=3; IntAct=EBI-18013275, EBI-12033434;
CC Q7Z7G2; P21145: MAL; NbExp=3; IntAct=EBI-18013275, EBI-3932027;
CC Q7Z7G2; Q13021: MALL; NbExp=3; IntAct=EBI-18013275, EBI-750078;
CC Q7Z7G2; Q9Y2E5: MAN2B2; NbExp=3; IntAct=EBI-18013275, EBI-12243024;
CC Q7Z7G2; O43451: MGAM; NbExp=3; IntAct=EBI-18013275, EBI-2829774;
CC Q7Z7G2; Q9NZG7: NINJ2; NbExp=3; IntAct=EBI-18013275, EBI-10317425;
CC Q7Z7G2; Q8N912: NRAC; NbExp=3; IntAct=EBI-18013275, EBI-12051377;
CC Q7Z7G2; Q8IXM6: NRM; NbExp=3; IntAct=EBI-18013275, EBI-10262547;
CC Q7Z7G2; Q9P0S3: ORMDL1; NbExp=3; IntAct=EBI-18013275, EBI-1054848;
CC Q7Z7G2; Q9UHJ9-5: PGAP2; NbExp=3; IntAct=EBI-18013275, EBI-12092917;
CC Q7Z7G2; P26678: PLN; NbExp=3; IntAct=EBI-18013275, EBI-692836;
CC Q7Z7G2; Q04941: PLP2; NbExp=3; IntAct=EBI-18013275, EBI-608347;
CC Q7Z7G2; Q5VZY2: PLPP4; NbExp=3; IntAct=EBI-18013275, EBI-10485931;
CC Q7Z7G2; P54315: PNLIPRP1; NbExp=3; IntAct=EBI-18013275, EBI-8652812;
CC Q7Z7G2; Q59EV6: PPGB; NbExp=3; IntAct=EBI-18013275, EBI-14210385;
CC Q7Z7G2; P43378: PTPN9; NbExp=3; IntAct=EBI-18013275, EBI-742898;
CC Q7Z7G2; Q5QGT7: RTP2; NbExp=3; IntAct=EBI-18013275, EBI-10244780;
CC Q7Z7G2; O75396: SEC22B; NbExp=3; IntAct=EBI-18013275, EBI-1058865;
CC Q7Z7G2; Q9Y6D0: SELENOK; NbExp=3; IntAct=EBI-18013275, EBI-9679163;
CC Q7Z7G2; P11686: SFTPC; NbExp=3; IntAct=EBI-18013275, EBI-10197617;
CC Q7Z7G2; Q9BRI3: SLC30A2; NbExp=3; IntAct=EBI-18013275, EBI-8644112;
CC Q7Z7G2; Q8IWU4: SLC30A8; NbExp=3; IntAct=EBI-18013275, EBI-10262251;
CC Q7Z7G2; P78382: SLC35A1; NbExp=3; IntAct=EBI-18013275, EBI-12870360;
CC Q7Z7G2; Q96G79: SLC35A4; NbExp=3; IntAct=EBI-18013275, EBI-12363689;
CC Q7Z7G2; Q969S0: SLC35B4; NbExp=3; IntAct=EBI-18013275, EBI-10281213;
CC Q7Z7G2; Q9NVC3: SLC38A7; NbExp=3; IntAct=EBI-18013275, EBI-10314552;
CC Q7Z7G2; Q9NUM3: SLC39A9; NbExp=3; IntAct=EBI-18013275, EBI-2823239;
CC Q7Z7G2; Q9NRQ5: SMCO4; NbExp=3; IntAct=EBI-18013275, EBI-8640191;
CC Q7Z7G2; Q13277: STX3; NbExp=3; IntAct=EBI-18013275, EBI-1394295;
CC Q7Z7G2; Q9UNK0: STX8; NbExp=3; IntAct=EBI-18013275, EBI-727240;
CC Q7Z7G2; P57105: SYNJ2BP; NbExp=3; IntAct=EBI-18013275, EBI-1049004;
CC Q7Z7G2; P02787: TF; NbExp=3; IntAct=EBI-18013275, EBI-714319;
CC Q7Z7G2; A0PK00: TMEM120B; NbExp=3; IntAct=EBI-18013275, EBI-10171534;
CC Q7Z7G2; Q9Y6G1: TMEM14A; NbExp=3; IntAct=EBI-18013275, EBI-2800360;
CC Q7Z7G2; Q9NUH8: TMEM14B; NbExp=3; IntAct=EBI-18013275, EBI-8638294;
CC Q7Z7G2; Q96HH6: TMEM19; NbExp=3; IntAct=EBI-18013275, EBI-741829;
CC Q7Z7G2; Q5SNT2-2: TMEM201; NbExp=3; IntAct=EBI-18013275, EBI-11994282;
CC Q7Z7G2; Q969S6: TMEM203; NbExp=3; IntAct=EBI-18013275, EBI-12274070;
CC Q7Z7G2; A2RU14: TMEM218; NbExp=3; IntAct=EBI-18013275, EBI-10173151;
CC Q7Z7G2; Q8NBD8: TMEM229B; NbExp=3; IntAct=EBI-18013275, EBI-12195227;
CC Q7Z7G2; Q9BU79: TMEM243; NbExp=3; IntAct=EBI-18013275, EBI-12887458;
CC Q7Z7G2; Q8TBM7: TMEM254; NbExp=3; IntAct=EBI-18013275, EBI-11956809;
CC Q7Z7G2; Q0VDI3: TMEM267; NbExp=3; IntAct=EBI-18013275, EBI-17555467;
CC Q7Z7G2; Q9H2L4: TMEM60; NbExp=3; IntAct=EBI-18013275, EBI-2852148;
CC Q7Z7G2; Q9BSE2: TMEM79; NbExp=3; IntAct=EBI-18013275, EBI-8649725;
CC Q7Z7G2; Q8N2M4: TMEM86A; NbExp=3; IntAct=EBI-18013275, EBI-12015604;
CC Q7Z7G2; Q5BJF2: TMEM97; NbExp=3; IntAct=EBI-18013275, EBI-12111910;
CC Q7Z7G2; Q9Y228: TRAF3IP3; NbExp=3; IntAct=EBI-18013275, EBI-765817;
CC Q7Z7G2; Q5TGU0: TSPO2; NbExp=3; IntAct=EBI-18013275, EBI-12195249;
CC Q7Z7G2; Q5BVD1: TTMP; NbExp=3; IntAct=EBI-18013275, EBI-10243654;
CC Q7Z7G2; Q9Y5Z9: UBIAD1; NbExp=3; IntAct=EBI-18013275, EBI-2819725;
CC Q7Z7G2; O75379: VAMP4; NbExp=3; IntAct=EBI-18013275, EBI-744953;
CC Q7Z7G2; O95183: VAMP5; NbExp=3; IntAct=EBI-18013275, EBI-10191195;
CC Q7Z7G2; Q9BQB6: VKORC1; NbExp=3; IntAct=EBI-18013275, EBI-6256462;
CC Q7Z7G2; Q14508: WFDC2; NbExp=3; IntAct=EBI-18013275, EBI-723529;
CC Q7Z7G2; Q96EC8: YIPF6; NbExp=3; IntAct=EBI-18013275, EBI-751210;
CC Q7Z7G2; O95159: ZFPL1; NbExp=3; IntAct=EBI-18013275, EBI-718439;
CC -!- SUBCELLULAR LOCATION: Synapse {ECO:0000250|UniProtKB:Q80WM3}. Cell
CC membrane; Lipid-anchor {ECO:0000250|UniProtKB:Q80WM3}. Note=Enriched at
CC the synaptic terminal. {ECO:0000250|UniProtKB:Q80WM3}.
CC -!- PTM: Farnesylation mediates presynaptic targeting and is important for
CC function in neurotransmitter release. {ECO:0000250|UniProtKB:Q80WM3}.
CC -!- SIMILARITY: Belongs to the complexin/synaphin family. {ECO:0000305}.
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DR EMBL; AY286502; AAP41128.1; -; mRNA.
DR EMBL; AK123184; BAC85549.1; -; mRNA.
DR EMBL; BX640655; CAE45797.1; -; mRNA.
DR EMBL; AB593158; BAJ84090.1; -; mRNA.
DR EMBL; CH471096; EAW63095.1; -; Genomic_DNA.
DR EMBL; BC106887; AAI06888.1; -; mRNA.
DR EMBL; BC106888; AAI06889.1; -; mRNA.
DR CCDS; CCDS11973.1; -.
DR RefSeq; NP_857637.1; NM_181654.3.
DR AlphaFoldDB; Q7Z7G2; -.
DR SMR; Q7Z7G2; -.
DR BioGRID; 130863; 101.
DR CORUM; Q7Z7G2; -.
DR IntAct; Q7Z7G2; 100.
DR STRING; 9606.ENSP00000299721; -.
DR PhosphoSitePlus; Q7Z7G2; -.
DR BioMuta; CPLX4; -.
DR DMDM; 74750239; -.
DR MassIVE; Q7Z7G2; -.
DR PaxDb; Q7Z7G2; -.
DR PeptideAtlas; Q7Z7G2; -.
DR PRIDE; Q7Z7G2; -.
DR ProteomicsDB; 69540; -.
DR Antibodypedia; 42122; 72 antibodies from 15 providers.
DR DNASU; 339302; -.
DR Ensembl; ENST00000299721.3; ENSP00000299721.3; ENSG00000166569.8.
DR GeneID; 339302; -.
DR KEGG; hsa:339302; -.
DR MANE-Select; ENST00000299721.3; ENSP00000299721.3; NM_181654.4; NP_857637.1.
DR UCSC; uc002lhy.4; human.
DR CTD; 339302; -.
DR GeneCards; CPLX4; -.
DR HGNC; HGNC:24330; CPLX4.
DR HPA; ENSG00000166569; Tissue enriched (retina).
DR MIM; 609586; gene.
DR neXtProt; NX_Q7Z7G2; -.
DR OpenTargets; ENSG00000166569; -.
DR PharmGKB; PA134902350; -.
DR VEuPathDB; HostDB:ENSG00000166569; -.
DR eggNOG; ENOG502RY7Q; Eukaryota.
DR GeneTree; ENSGT00950000182938; -.
DR HOGENOM; CLU_141096_0_0_1; -.
DR InParanoid; Q7Z7G2; -.
DR OMA; MGQFQNL; -.
DR OrthoDB; 1441014at2759; -.
DR PhylomeDB; Q7Z7G2; -.
DR TreeFam; TF331867; -.
DR PathwayCommons; Q7Z7G2; -.
DR SignaLink; Q7Z7G2; -.
DR BioGRID-ORCS; 339302; 4 hits in 1064 CRISPR screens.
DR ChiTaRS; CPLX4; human.
DR GenomeRNAi; 339302; -.
DR Pharos; Q7Z7G2; Tdark.
DR PRO; PR:Q7Z7G2; -.
DR Proteomes; UP000005640; Chromosome 18.
DR RNAct; Q7Z7G2; protein.
DR Bgee; ENSG00000166569; Expressed in cerebellar cortex and 12 other tissues.
DR ExpressionAtlas; Q7Z7G2; baseline and differential.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0043195; C:terminal bouton; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IEA:InterPro.
DR GO; GO:0046928; P:regulation of neurotransmitter secretion; IBA:GO_Central.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR GO; GO:0016079; P:synaptic vesicle exocytosis; IBA:GO_Central.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR InterPro; IPR008849; Synaphin.
DR PANTHER; PTHR16705; PTHR16705; 1.
DR Pfam; PF05835; Synaphin; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Exocytosis; Lipoprotein; Membrane; Methylation;
KW Neurotransmitter transport; Prenylation; Reference proteome;
KW Sensory transduction; Synapse; Transport; Vision.
FT CHAIN 1..157
FT /note="Complexin-4"
FT /id="PRO_0000240235"
FT PROPEP 158..160
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000240236"
FT REGION 14..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 157
FT /note="Cysteine methyl ester"
FT /evidence="ECO:0000250|UniProtKB:Q80WM3"
FT LIPID 157
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000250|UniProtKB:Q80WM3"
SQ SEQUENCE 160 AA; 18336 MW; E812EE05BD47E179 CRC64;
MAFLMKSMIS NQVKNLGFGG GSEENKEEGG ASDPAAAQGM TREEYEEYQK QMIEEKMERD
AAFTQKKAER ACLRVHLREK YRLPKSEMDE NQIQMAGDDV DLPEDLRKMV DEDQEEEEDK
DSILGQIQNL QNMDLDTIKE KAQATFTEIK QTAEQKCSVM
