CPNA2_CAEEL
ID CPNA2_CAEEL Reviewed; 7705 AA.
AC Q09221; D7SFI9; Q10908; Q27GU7; Q5WRU1; Q5WRU2; Q5WRU3;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 21-SEP-2011, sequence version 4.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Copine family protein 2;
GN Name=cpna-2; ORFNames=B0228.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP TISSUE SPECIFICITY.
RX PubMed=16038089;
RA Zhao Y., Johnsen R., Baillie D., Rose A.;
RT "Worms in space? A model biological dosimeter.";
RL Gravit. Space Biol. Bull. 18:11-16(2005).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=c;
CC IsoId=Q09221-1; Sequence=Displayed;
CC Name=a;
CC IsoId=Q09221-2; Sequence=VSP_041755;
CC Name=d;
CC IsoId=Q09221-4; Sequence=VSP_041756, VSP_041757;
CC Name=e;
CC IsoId=Q09221-5; Sequence=VSP_041754;
CC -!- TISSUE SPECIFICITY: Expressed in body wall muscle.
CC {ECO:0000269|PubMed:16038089}.
CC -!- SIMILARITY: Belongs to the copine family. {ECO:0000305}.
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DR EMBL; FO080130; CCD61447.1; -; Genomic_DNA.
DR EMBL; FO080130; CCD61455.1; -; Genomic_DNA.
DR EMBL; FO080130; CCD61456.1; -; Genomic_DNA.
DR EMBL; FO080130; CCD61457.1; -; Genomic_DNA.
DR RefSeq; NP_001021884.1; NM_001026713.2. [Q09221-4]
DR RefSeq; NP_001040723.1; NM_001047258.1. [Q09221-5]
DR RefSeq; NP_495623.2; NM_063222.2. [Q09221-2]
DR RefSeq; NP_495625.3; NM_063224.3. [Q09221-1]
DR SMR; Q09221; -.
DR STRING; 6239.B0228.4c; -.
DR EPD; Q09221; -.
DR PaxDb; Q09221; -.
DR PeptideAtlas; Q09221; -.
DR PRIDE; Q09221; -.
DR EnsemblMetazoa; B0228.4a.1; B0228.4a.1; WBGene00015061. [Q09221-2]
DR EnsemblMetazoa; B0228.4c.1; B0228.4c.1; WBGene00015061. [Q09221-1]
DR EnsemblMetazoa; B0228.4d.1; B0228.4d.1; WBGene00015061. [Q09221-4]
DR EnsemblMetazoa; B0228.4e.1; B0228.4e.1; WBGene00015061. [Q09221-5]
DR GeneID; 174250; -.
DR KEGG; cel:CELE_B0228.4; -.
DR UCSC; B0228.4a; c. elegans. [Q09221-1]
DR CTD; 174250; -.
DR WormBase; B0228.4a; CE31282; WBGene00015061; cpna-2. [Q09221-2]
DR WormBase; B0228.4c; CE44996; WBGene00015061; cpna-2. [Q09221-1]
DR WormBase; B0228.4d; CE37471; WBGene00015061; cpna-2. [Q09221-4]
DR WormBase; B0228.4e; CE39660; WBGene00015061; cpna-2. [Q09221-5]
DR eggNOG; KOG1327; Eukaryota.
DR GeneTree; ENSGT00940000168644; -.
DR HOGENOM; CLU_222795_0_0_1; -.
DR InParanoid; Q09221; -.
DR OMA; KYDAMKM; -.
DR OrthoDB; 1067545at2759; -.
DR PRO; PR:Q09221; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00015061; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR CDD; cd01459; vWA_copine_like; 1.
DR InterPro; IPR010734; Copine_C.
DR InterPro; IPR002035; VWF_A.
DR Pfam; PF07002; Copine; 1.
DR SMART; SM00327; VWA; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..7705
FT /note="Copine family protein 2"
FT /id="PRO_0000065046"
FT DOMAIN 7475..7673
FT /note="VWFA"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4381..4427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6779..6800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1301..1331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4398..4414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6779..6797
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..5003
FT /note="Missing (in isoform e)"
FT /evidence="ECO:0000305"
FT /id="VSP_041754"
FT VAR_SEQ 1258..7329
FT /note="Missing (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_041755"
FT VAR_SEQ 1348..1379
FT /note="DEHGLEPDQQVSKQLSSIERQLLKLDEVVIGN -> SSSVRSSSIYIELGDD
FT MEIICEHNTKQAILVY (in isoform d)"
FT /evidence="ECO:0000305"
FT /id="VSP_041756"
FT VAR_SEQ 1380..7705
FT /note="Missing (in isoform d)"
FT /evidence="ECO:0000305"
FT /id="VSP_041757"
SQ SEQUENCE 7705 AA; 858095 MW; A8DE2895BD181465 CRC64;
MNDYEIRDLT GSSQKSNNQK ISNNSGESAH FNGTSENVKT ESDDDSTCSS SLNKLSNRHS
EPMNHLSVGG FVAKDLLSSL TIPLPQTVIR TCQSIDIDTP DRSRNDKTLT SFFYSSCKNL
LLTTIIPDPL DLVAAAVGQS TAQALLVAQI GWMVCVCCRC CLCKCIANGR GVRGQKKQIQ
EPTIADDDGR DLPYEVPGSI HIPKPVYNKK LSKSRSSSVP HVSVPSLVSS SADYKRLSMW
ETSLNVESDV EPLHTPPLVV GRKLDYIDKE GNNPSCCRER GTRKPGFRPL RGSGSPPPPD
PSTSTKVAVT SASEVKKIKD HKKQLKKEKE KKKKMDKKQS SSGGGFFTRW FGGSGSNNSQ
QNLAEDVIDA RSERKTAKQR EQELLQRSER RSGGRTHSHE EYRRHQQPSL MVNTNFDEDD
YATIDRVRRS NNREMSMPAS PRNVHFVDET SGPLSRTMNE SAFGDRAHLQ YRPRAQKGAA
GPTTRGAPTS SVNQLDEATL DLLRLSTEPS PVPSRRALPK SASLSSVQQK QPIKTADGGQ
LKIGSVYTWD QNSVDTTTDD ERAKDFLRGD RSSRLSPQSE RKNERQIQIR QQSSGPTNRR
ETEIEYEEKR QGPPVVRTTV EGKLKMEKIV GADLITVDSC ISSAWTVRDT VTNYKIKSTI
GKKSLILEEI KDGQSKYKIT LIENGETKME REASLDVPDF VNKKDYLAEV SKKLLSDLRE
DSESVSALTH IEVEIVEDVT NILKTYVIGE RADDVLAEEQ LRLHYEQTAD KTPSPIPLEK
VEKIYVDELQ KDKIELEDPE KADIHLIKDG RHFEGEGALK RIRRFETEES IEKPTVIRME
PRCAHAFADC DVAKKDDTSN YTVKIAVPLV HTITFLLKKS KMMRQQKAAG YEMEQEGQRF
EDETTLRRIK RYETEEEEEK QHVAVIQHVE EVKVATMKTQ REVEAEGGQY EMSQEGIHLR
GETTFKKRGK HLDSESSEER FMEREAEGGQ YAMQMEGERL LGEKKFRSKG RHYESESEES
MASWNGGSPT LVDLVKKESS SIFEATFETA NNHSPIVAEV RRPKLKKENT TIGCTISNQK
ATSANAELTT KHVNTEKGSG KFRELGEEQA MMLCGFENQK SSKEEVTGSR QQKNEIKVAF
AAGSAETENT TISTTIFHDA DSFAVEGSSK SANSTATYGR FKEMSEENAS NMVYLQKSES
SSSNLSGAET KMKHIQRQSS EARFSEFKQV AESCAVMIKN TGVERGSTSS TVAEAATDLR
IRRKDAKGEI IVFVLFKRVF GNYVHASMRL ASSGSGLLRE NRSELREMRS EEKRSNSMHH
EESHYAHSSY EHTSEHYSQS SFYHQESDEH GLEPDQQVSK QLSSIERQLL KLDEVVIGNE
CTDVVEVKVT IKKREQNANQ LIVVLEELLE TAICGGIREI KRSIVDTSLE SRVRKLEQSS
LYSIIKKSSS KESVVHCGKP PLERQASLEG RFRMEESWSA VECKRRSSSI DRASLKLRAS
QEEVCTGFWN TSKGESTRRT ILQKTKSVES MCLKTKSASS TSIDMFSDCQ RATVSQTIST
EIASHRREIV AAAFGISTQS LERLLKFVEI IDWENITMNV SQKEQLSANL QALTSAPVNL
DIPSDLGRIV APAEQDAYSD LIMRERAESR VFAQLRASAD EITIREVALG SMSQLEQAAF
MSLLITSVSR CDLRTIAPSN IIANTEIFYD VAEEKMSVSG VMKRESRKEH SSKKFTSSRE
EIIQGFWKGE RDEERVVKTL KDRMVSFKHS LSVEAASSTS ENVSLGMRKA DQKSEFTISQ
KLSPKEIVSE AYGVSESKLD QFFQVMEKMD WSNIELGEKE HTALSANIRT LAPEQKVCDG
ILGKLKAPKQ QDESVGTQIQ EIRRATAVMS VRASLLLTIS SNSNFSKNIS DSEKAVFSNL
ISVITSHNLS TIGTSSETTT ASISYQDIPE MLAASKLWIS RNSEKLKKEI REPVIQTVES
FWNTTNDQEK VAVLLNEKID SIYSSLNTLA ASMENEIISQ ELVRHTENAG KVNIKPISPR
ELVSSSFKIT SSDLQQFFNV LEKMDWSQIS LPAQEHAIIS KNVRSLAPSA SELSNILGKL
RAPEMQEETT DLKIRQAQQA RVVLNVSESM SNTISSSETF SRIPENKKAT LTNLVGIITT
QDLSTLGASS ENQTIEMDYT EAKEELEASK KLVDKNLSVL KTEIRESGDE VVQGFWNTAS
DKEKVGAIIC EKLKSIHHTL HTHAIRTVTE SLSTDIQKEQ QKLSTHHFVK LSTRDVVQAA
FRISSESVDH LLTLVEKMDW SKIDLVEPVY SNISSNVQAL ATSSSQSSGI LGKLLPPAPE
EETTSKEIRE INTAKCILNV ISSLNSTITS DASLDMISES EQAIFSNIIG VMASNNLTTS
SQSTSSSFGF NNVFELSEAR RVLQESNKQN LIQKVRESSE ELIHGIWSTA SETEKVAIVV
KEKLETVHQA MKTLAIQMAT QSVNSELIGS EGNLASIKSI TLPTREVISA AFGISNEVIQ
KMLEVLTKGE WSTISLPQSE YESISQNVRA LAEPSFNCDS ILGKINAPGP QTETTSHELI
EKNTAAAVAN VKAAVESVIS KESSLAKLPA DEKAIITNLA GLVLSKDVSS LCTSSETFGF
DQRIFRNQNA NISLGAVRSE TLLQRLREPI ENQVQGFWST ASNQEKASFI AKQKLDTMYD
TMKVIAIQMI SQTIDGDFSS ASISSETFKN IDKAAREVVA AEFGIANESV QKALEVLNKV
EWSDISLPEK LHQNISSNVR VLADSSYNCD SIIGKLNAPE PQSAYVDQQI SEHQTLEVIA
NIKSAVSSVI SNDSVLSKRS EDEKAVISNI ANLIISCDLA SMSSTSNSFE FQRDILEPQN
ANVLLGTPAS QVFTRNLQEP IQSEVQGFWS TNSSQEKASL VIRQKLNVKY DAMKMMATEI
AYQSLNSNIT SEETNLESQK SFDKSIRESI MASFGVSSEH VQKTLEILSK SELSTIVLPA
VEYEATVQNI KALSEPNFNC ESILGKLNAP DPQSAVMDII MNEQRKLTVV SNIQSAIESV
ISNDSSLEKL TEVDKSVILK ISEIIVSHDL TALSSSCSDF NLLQESNTQE KADIFLKTPN
SQMLIERLRE PIEKQVQGFW STASNSEKQE MFLKEKVETI HAMLQTFSAS LVSETVQRDF
MATVQSLAAL RSIQLTPREI LCAAFGISNE QIEQTFRGLD EVDWSHIDIP CALRDNLLVN
LRIVNADAPN VFGNLISRPD ENQETSTVLE EKNRIQFLLN LQRSLDQTVQ MTSSLTRSDE
RIEVKVSNII SLISSENLGD LISQAVQLAQ PNMSDETEKS FEIPRNILLN RVVPETSEES
IQSFWKTSQL AEEASSTISE KLSMLQSEFV VSAAKQVSTS LTLDYRRKIF NQNSEIIFGD
LTRDVVKAAF SVSDETLNTL FSQLEQSDWS QIKLSSKQKS ILSANIKSLA TSNLDTLIGQ
LMPREADSEQ SEASLSERSS VEMENTFKIQ QIIFDTVVRK FGSDEERASI INLIGLLTSV
NLKAAIQVAS FERLPDSLDS TASITPVFKI QEHVRQPTEQ VVQGFWSKER HPNETVEVVN
RKIEVLKSIL NCYAVAECHK SLERSLEKPS QQDETCATRG VTEVVQNAFA VTEQSYSKIL
KVLGSMQNFE IPEAVKETIS KNLKILNLPP VDTLLVSKYK ESHVSKTVEE QELVQFMFNF
KSALNSEIEM SQNVSKCIEE ETVVLPNLVA ILASANLATI VPTESRQLSD SENILNFSIQ
HEESERSAAT VRDEINILRH YLQTFAIQKA SSEVSRVIEI IKTSQSFHLV HTTMLEEIKT
IQLRMEVLKR VSMNQSTAEE LLQEAFQNSE QQMETFQRIV QNVHWEETKL TEEIIRNLRI
NMTAIPRFES TVGSLKAPDD QHESADSYIS STRRAEAVIN LMAAADNAIS TSSTLSMMES
DERLLHKTIL KTMAVCNLTT PASRSETETM TQGFYQKVEQ CQTEQELAER PKINCEMKVL
EISDDEVHGI WSSRKEQESS QKILLASELE KATLQTLASG DETNSIYTEL ASFGTREEIE
KLVSIELRDI VEKSFGVSEE SLNKLLNLIP KMDWSSLTMP IVQKELVIKN LALLLPAEAL
IMESVGTIQA PPEEEAFAEL DLKQAREAKV MMDIQECVFT TCTGYTEMNK PDDAEITTFS
ALLGTLSICD LVTMASSNIQ VDSKYDYYRR PAPKNAETTF TESNADAFSL ALQEAGEVTS
SGIWSTVSNS DAAKTTVSDK LISISKTEMS MKAVSENAVN QDHSLKKDSI EAVEMNIPDS
RKEILQKNYS IDRSNSTVEM QGAIASEDIA IQYSAPRVDN VSQTMRSQSQ KDLLFGGSFG
ELEPPLPQEE DVETTARQSR VYRSSSQVRA PSEESIQKTE ALRRSESLES NARKTFVDRR
RENVSLSRKA SVERETNMEA RVAKADQSIP VETLQKSKKQ ESIFSSVVES KDLNVCGSWT
TAKPPIGAKV SLQTKKVEKE VTSATMTVAS ASVECEVGLE SKREQSRDAT GSMVRAKSIE
EVEREFGVEV TSTEKTLEKR DQIESWIKSI PQRLEVEESA EFGNDEVIIG GVMGSLEAPL
EQEEETEKLL TMKRSASEAR SLKAATKESI EEADEFSKIE ADQEILTVQK ELVKATGILN
AAASREINAS SKMEYSKVPS EDVIELSLTE SRRQSNSGQF KETKEEEIVG LWNTGTKGEN
ASKVLPHKPP IDTASMKAKA AKQNSIEMTG SLQKSPSAEA MGIVSQKVTE GANSKFGIAQ
GAVETTLTAS AQSGVTCRDI SVSNIGVASE TVTQFSNKET GIGFGASNLI APPPESAETE
FTGKISNLSQ TSLNKMAASD VGTTVESKIQ APGDNYGDVS LLQKVASSDA ITKAMQASRD
SAISVDFRQD RETVSAEKSD LNFKSTNSET QKLKLFESKE EESGIFIRSS HEYEETQKTL
RHRSASRESA SRTVTAPTNQ EVQMNFDKKV EDSVAEGSLS IGIVRESSQS EVMQHAERTS
ELTKLSMNEE VAGVRAVSET TNETFRGYQQ GDVEVQTGAA MGRIEAPRPQ RGEAEITQKL
RRTLSVERSA KASEMAESQT VTQIQKREDS LASEYSVRDT LLLKSSSVSH VATEQMSEHL
VMRSKSEHHI SEKLQERLIE KESFSSQEFI SENQGVHTHW DVIDNNGDAL ICWKSSETEQ
KSLDAKQVTE ELAGTTLDLS VRLLGGTDEE KIAEHVIVGA SEVLNISETR ADMEMSRQDA
FSDDATYVAS DILEERSLST VHEFGESEAS TTFGVGKLVT KKPEKEEVGR SFSETRKLSQ
FSDITAISET TTDMDSEILR LPECDQSVTL ISHKNQQKDV KDLKATVENT ADQVTLLEKR
EVREQSADVK KKKFEVEDIE EVLPMIRRWA EILSMKASTS VEIQAENKLS KPEAQAESQK
YLKTANLEIN KINVNATHEE VMSATTALEC KTSGQDVASI RLRDKSRERV EKKYQENQWN
LLSTNAEWET LLNDLEDSVT IAQSVQDSMA FSVKASATVN LNSDTSIKKA QPEIGIQKSI
SQSNVEKTVG QFSSATIGNE LLVTRLGMDL EEIETLVDEI NREQAVGGRI REFGKSETGG
GIYLVRRALP KVKETSTHTV TVATSFRQIF STMSAGDEIS EANVELTIPS TSVGAEIKST
VARSDSMTFS TSHASEYTAS TVADYARDIA VSASTAARKK AIPTERTSQK LKEVGADGIE
ILSLWEGIET DLDATTQLVD LLRVKSSLQT IESSEEVERI NQYLEMPEEK GLVIHLINVQ
NKETCERNFA VSICSLDTVH SRKSEIPPTY SVSKVLTEKR VLRETWRVIE SGDVRFNAVI
NLHRYSLSKP TLAQETVLRE VVRIAAQPLF ISAEPTYMRT KESSEDIVGV GIAYNVPEEN
LISAIKLDEK ASGGCYELTT KAAGDEYKMI SSILSKTQAV EKVKGKMIQK VVAKDEIRVL
ETTTESVNAN FNYEIPEENF KIGIAKTCAN NAAPFTMRLH ECLDFYVKMF YNMNKKDDFE
SLIKTIIISN GIESKTLSCT AAEHIEATRN PEFNRPAEFS DIQKTVVDYN KIEGASLNTF
EALNEKMALS TMLSRQDDYS RVEHIVKDKN RGANLKFRFI ESSEEKQTTF SAFEIDTEKE
EIERTIDLVR QGGQFKLSTD AAEENEITLH RDISKPIITH YDTLHLITLS NSAPHQILST
SGASNELHTI STQLSKPAEW LNTELLIVDK NVEQPVTWRV LECEECVENL HPIYRRPDDI
FDLDEIWHIA RNGGKFERRC KASGDEKEIF EQEIKSRGIK DDIIDKKFIV GNQGEPTSFT
TIQTSSVSAS VSQDMSRLGE KEAIKKVLQN SNKGINVEKK MIEATEYRET ISEQFRKNDE
FDKADLTVKD RRAGGSYELS TNASEQSSSS VSNELICPRP SQLSIEKTFI TAQTIIPAIL
SCKASESIGH TISEQWNRPN DQFAISQIVK DCNKENEQFT FREAGEEYHT TNCFYTREQE
EKVIAKTLHE ARKGSGQTFE TKHATDRSMD ASQHLEKDRL AEATAEKLFV IGNTAGPVSY
SSKSSSDIQH SQVVNLSRPS PYVQVEIIRK GANLGTPTYF HARETTSKTE NVATQLSRKE
EKMEVSTTHT TPLLAEPVTF DSNASKSHST SLDKNLVASE DYELDAVVII VDNNTEQPQF
FRCSCTKEAS TSAAAALSAG SKSESCKIVR LASNLGHPTS LVLCESSSVQ ETNNVHYQRD
EHHEHISETK SYPRDGGKFT LDTKASTANE VRIDKDLEKK SDRELETEIK TIVRNEGEPV
EIFVSATEES AAGVTTSLSR ANPFESANIL LTSPNKGEPA YSRVTESSEL TETNNVQLRR
EEEHQETEKI IEIAANGGSS LLRAGFADEK FADIEAKLGK DAQFESAQTI RQIGNEDKTN
LSIGASQETS VTFDETVQCN KSSCEETSIT KVAKNIEPHV IFRSTEASDM AVGIHYTLRS
SEKVEETEEI KNIARNGGSA TFSCFASGDE SPDSVSAFLT RQPQEETTEK LFPTPMFDFI
KFNSTAAEEF AVWNTTIFRR KDNEGEVEKI FNTSEAGHNE TFSANAAEDV SVTLDADLHF
GVGYKEHRQI TKDEANQGEG TGMHSGASEE TIFNLGYDYC KQPTEFTTVC VTEDKLLIQG
AYGFRAAKEE SITLDADLHF GVNYRDLLAM GLHASNNEIE GTGMRSTASE ETIFNLAYDY
CKQPTEFRTV FVSEDHQFVH GAFGFRAVGE EHIETQVLEL QARMVEVMVE GSVHNLARRH
EDEPFVLYTE VIEETIIRVD EQLEKKTTVI ETEQASEVKM REKGEERRKE EKRVSFAAEV
QEKTMEAIDK SLGLDTSMEV EPAFQKPSII KKPMKKERER RSRDLRQNAA PAFKPVRRNS
LLQALAIGSP HNIPHFKTLD DIVKAIKHAG LEYSNLIFGI DYTKSNFYQG ERTFDKRPLH
TIDPAEMNPY QQVIQIVGKT LSSFDADGQI PAYGFGDEEF TDHGIFNIAE RYDLEKDCNG
FEEVLRVYNE VTPTIEMSGP TNFVPLIDRA IEICKEKHSY HILVIVADGQ VTNEKINQKA
IAAASHYPLS IIMVGVGDGP WNMMGRFDDN IPKRLFDNFH FVDFHKVMFN APNADASFAL
NALMEIPDQY KAIKELGLLK HSRRG
