CPR49_ARATH
ID CPR49_ARATH Reviewed; 256 AA.
AC Q9SRM5; Q8LDB1;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=GDSL esterase/lipase CPRD49;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase CPRD49;
DE Flags: Precursor;
GN Name=CPRD49; OrderedLocusNames=At3g11210; ORFNames=F11B9.13, F9F8.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=16055634; DOI=10.1105/tpc.105.033985;
RA Nakayama N., Arroyo J.M., Simorowski J., May B., Martienssen R.,
RA Irish V.F.;
RT "Gene trap lines define domains of gene regulation in Arabidopsis petals
RT and stamens.";
RL Plant Cell 17:2486-2506(2005).
RN [8]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in anthers (stages 8-12).
CC {ECO:0000269|PubMed:16055634}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC009991; AAF01505.1; -; Genomic_DNA.
DR EMBL; AC073395; AAG50959.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75014.1; -; Genomic_DNA.
DR EMBL; BT024775; ABD59113.1; -; mRNA.
DR EMBL; AK228873; BAF00764.1; -; mRNA.
DR EMBL; AY086102; AAM63310.1; -; mRNA.
DR RefSeq; NP_566387.1; NM_111956.3.
DR AlphaFoldDB; Q9SRM5; -.
DR SMR; Q9SRM5; -.
DR STRING; 3702.AT3G11210.1; -.
DR PaxDb; Q9SRM5; -.
DR PRIDE; Q9SRM5; -.
DR ProteomicsDB; 224493; -.
DR DNASU; 820291; -.
DR EnsemblPlants; AT3G11210.1; AT3G11210.1; AT3G11210.
DR GeneID; 820291; -.
DR Gramene; AT3G11210.1; AT3G11210.1; AT3G11210.
DR KEGG; ath:AT3G11210; -.
DR Araport; AT3G11210; -.
DR TAIR; locus:2074688; AT3G11210.
DR eggNOG; KOG3035; Eukaryota.
DR HOGENOM; CLU_051989_0_2_1; -.
DR InParanoid; Q9SRM5; -.
DR OMA; FANGGWG; -.
DR OrthoDB; 1226154at2759; -.
DR PhylomeDB; Q9SRM5; -.
DR PRO; PR:Q9SRM5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SRM5; baseline and differential.
DR Genevisible; Q9SRM5; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR045136; Iah1-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR14209; PTHR14209; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..256
FT /note="GDSL esterase/lipase CPRD49"
FT /id="PRO_0000367326"
FT ACT_SITE 15
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 213
FT /evidence="ECO:0000250"
FT CARBOHYD 49
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 79
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 243
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 115
FT /note="F -> S (in Ref. 5; AAM63310)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 256 AA; 28584 MW; 1403C848CC9F794C CRC64;
MVGPARPQIV LFGSSIVQMS FGHGGWGAIL SEVYARKADI ILRGYYGWNS SRALEVVDQV
FPKDAAVQPS LVIVYFGGND SMAPHSSGLG PHVPLTEYVD NMKKIALHLQ SLSDFTRIIF
LSSPPVDEAK VRQNQSPYLS EVIRTNDLCK TYSDACVELC QELGLEVVDL FSTFQKADDW
KTVCFTDGIH LSAQGSKIVA GEILRVVKEA EWHPSLHWKS MPTEFADDSP YDLVSADGKQ
TVNSSEWTYF WEEQWD
