CPRT_SBWMN
ID CPRT_SBWMN Reviewed; 754 AA.
AC Q89250;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 29-SEP-2021, entry version 60.
DE RecName: Full=84 kDa readthrough protein;
DE AltName: Full=CP-RT;
GN Name=CP-CP2;
OS Soil-borne wheat mosaic virus (strain United States/Nebraska/1981) (SBWMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Furovirus.
OX NCBI_TaxID=652673;
OH NCBI_TaxID=4513; Hordeum vulgare (Barley).
OH NCBI_TaxID=4564; Triticum.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=8317092; DOI=10.1006/viro.1993.1342;
RA Shirako Y., Wilson T.M.;
RT "Complete nucleotide sequence and organization of the bipartite RNA genome
RT of soil-borne wheat mosaic virus.";
RL Virology 195:16-32(1993).
RN [2]
RP IDENTIFICATION, AND FUNCTION.
RC STRAIN=-/Japan/JT/1982;
RX PubMed=11062037; DOI=10.1006/viro.2000.0587;
RA Yamamiya A., Shirako Y.;
RT "Construction of full-length cDNA clones to Soil-borne wheat mosaic virus
RT RNA1 and RNA2, from which infectious RNAs are transcribed in vitro: virion
RT formation and systemic infection without expression of the N-terminal and
RT C-terminal extensions to the capsid protein.";
RL Virology 277:66-75(2000).
CC -!- FUNCTION: Minor capsid protein involved in virus transmission by the
CC vector. {ECO:0000250, ECO:0000269|PubMed:11062037}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Associated with one
CC extremity of viral particles. {ECO:0000250}.
CC -!- MISCELLANEOUS: This protein is translated as a fusion protein by
CC episodic readthrough of the termination codon at the end of the capsid
CC protein. Readthrough of the terminator codon TGA occurs between the
CC codons for Ser-176 and Arg-178, thereby producing the 84 kDa
CC readthrough protein.
CC -!- SIMILARITY: Belongs to the virgaviridae capsid protein family.
CC {ECO:0000305}.
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DR EMBL; L07938; AAA48495.1; -; Genomic_RNA.
DR RefSeq; NP_049338.1; NC_002042.1.
DR PRIDE; Q89250; -.
DR GeneID; 991051; -.
DR KEGG; vg:991051; -.
DR Proteomes; UP000009270; Genome.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.120.70; -; 1.
DR InterPro; IPR001337; TMV-like_coat.
DR InterPro; IPR036417; TMV-like_coat_sf.
DR Pfam; PF00721; TMV_coat; 1.
PE 3: Inferred from homology;
KW Capsid protein; Reference proteome; Virion.
FT CHAIN 1..754
FT /note="84 kDa readthrough protein"
FT /id="PRO_0000409452"
FT REGION 106..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..735
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 83737 MW; 4F1B888667590C54 CRC64;
MAVNKGYTGY NKELNAMAAT HAYIRLSTLM SQIESWQATR ASVLTHLGVM LNGVSKLGER
SFFSRTKRFG AHTSDGDEIF CDLGGEAVTQ ILSRLTVALQ SARGEGAQTR NAKRGAAPGT
SQVENEEQGQ TDQTLAISNA VAELMIFVRT KDFTMNECYT QDSFEAKYNL KWEGSSXRDG
VSGKLRAQIV EEFQNRLIIA DDLGIFPRRD VDGVIIRNEP EVVYSELEDK LLSFESSVYH
PKAVTVEFEV PVATGTTTTD DEITTEDVEM VIVTEVLVDD ESDYYWLYFV LLLTSFLITC
FILLSRRFIH FLGNRGGPGA PLCRRFATRL WSIRLWLLRK ATRRYGNLGV VRKTHSQTTM
RKYLRDYNFQ LEEWETAIGC TPREALIVAD QHILVRAVQR IVDSVGDVDS VDAVRKVFNG
YKVRNFKIEK WLNKQTVNSA LAVLNDSTVP ENVVLSEGML SLQTATFEEV LRCNVESQRE
SAYFNELIAL QFAFRLVGTP EFSDFVLAYK GPAYPCYVEA INRHGTCIIQ HHVDEDQKRK
NDRAIEWLLM AGQGAFVVSS VVTTGVVVFK IHKWLKQRLL LRALSMLPSV GGGGNGGGGG
SLPPQALELF DRAGTFEERL AALQNGLDLS PENMEVFTPE ELKTEIRHVV QAYADSSYHV
ADEPYLRGVG VTVVTGLPEA VGEITTTGSE VSSVDTSISL GVPGRARRRA VSKNTRMYPS
TSGQSYNSYK SPRVSGKSGV GSMKMKIASK PMAS