ID   CPS2G_LACPL             Reviewed;         337 AA.
AC   Q88XJ7; F9UN01;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Exopolysaccharide phosphotransferase cps2G;
DE            EC=2.7.-.-;
DE   AltName: Full=Stealth protein cps2G;
GN   Name=cps2G; OrderedLocusNames=lp_1203;
OS   Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS   (Lactobacillus plantarum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=220668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA   Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA   Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J.,
RA   Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA   Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M.,
RA   Siezen R.J.;
RT   "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=22156394; DOI=10.1128/jb.06275-11;
RA   Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA   Kleerebezem M., van Hijum S.A.;
RT   "Complete resequencing and reannotation of the Lactobacillus plantarum
RT   WCFS1 genome.";
RL   J. Bacteriol. 194:195-196(2012).
RN   [3]
RP   IDENTIFICATION AS A STEALTH PROTEIN, AND PREDICTION OF FUNCTION.
RX   PubMed=16299590; DOI=10.1371/journal.pcbi.0010063;
RA   Sperisen P., Schmid C.D., Bucher P., Zilian O.;
RT   "Stealth proteins: in silico identification of a novel protein family
RT   rendering bacterial pathogens invisible to host immune defense.";
RL   PLoS Comput. Biol. 1:492-499(2005).
CC   -!- MISCELLANEOUS: Stealth proteins are part of a protein family that is
CC       conserved from bacteria to higher eukaryotes. Family members were first
CC       identified in microbes as proteins that help pathogens to elude the
CC       host innate immune system. Microbial stealth proteins are involved in
CC       the biosynthesis of exopolysaccharides. Stealth proteins are predicted
CC       to function as hexose-1-phosphoryltransferases.
CC   -!- SIMILARITY: Belongs to the stealth family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL935263; CCC78590.1; -; Genomic_DNA.
DR   RefSeq; WP_011101304.1; NC_004567.2.
DR   RefSeq; YP_004889104.1; NC_004567.2.
DR   AlphaFoldDB; Q88XJ7; -.
DR   STRING; 220668.lp_1203; -.
DR   PRIDE; Q88XJ7; -.
DR   EnsemblBacteria; CCC78590; CCC78590; lp_1203.
DR   KEGG; lpl:lp_1203; -.
DR   PATRIC; fig|220668.9.peg.1021; -.
DR   eggNOG; COG0438; Bacteria.
DR   HOGENOM; CLU_043224_1_0_9; -.
DR   OMA; IFKYWFR; -.
DR   PhylomeDB; Q88XJ7; -.
DR   BioCyc; LPLA220668:G1GW0-1033-MON; -.
DR   Proteomes; UP000000432; Chromosome.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR031358; Stealth_CR1.
DR   InterPro; IPR021520; Stealth_CR2.
DR   InterPro; IPR031357; Stealth_CR3.
DR   Pfam; PF17101; Stealth_CR1; 1.
DR   Pfam; PF11380; Stealth_CR2; 1.
DR   Pfam; PF17102; Stealth_CR3; 1.
PE   3: Inferred from homology;
KW   Exopolysaccharide synthesis; Reference proteome; Transferase.
FT   CHAIN           1..337
FT                   /note="Exopolysaccharide phosphotransferase cps2G"
FT                   /id="PRO_0000235946"
SQ   SEQUENCE   337 AA;  39970 MW;  AE8BEA9B376E8C56 CRC64;
     MRGFLMFTSG PFDIDFVVLW VDGSDEKWLQ KRAIYSSTKQ QNNAVRFRDY GIFKYWFRAV
     AKYAPWVHHV YLVTDEQIPN WLSIQNSKVS VIDHKSIMPE DALPTFNSSA IELNIANIPG
     LSEHFVYFND DMFLNRQVTP MDFFSEDGLP KDSAVQNAIM PVEDFDHMTA NNVMLINQNF
     NKYQVLRRHP FRFFNFRYGF LNVLSICLLP WPRFTRFQDP HVPISFRKSV FEKVLNLHRD
     AWNETSHNRF RNRNDNTIWL IRYYQLVTAQ FNPRTPFVGK KYNIGEMKKI VNDINTGKHK
     MICINDQNVS MAEFDNLTKQ LRSTFRSKLP QKSEFEK