ID   CPXN_NOSS1              Reviewed;         459 AA.
AC   P29980; Q59131;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 3.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Probable cytochrome P450 110;
DE            EC=1.14.-.-;
GN   Name=cyp110; OrderedLocusNames=alr1450;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2123860; DOI=10.1128/jb.172.12.6981-6990.1990;
RA   Lammers P.J., McLaughlin S., Papin S., Trujillo-Provencio C.,
RA   Ryncarz A.J. II;
RT   "Developmental rearrangement of cyanobacterial nif genes: nucleotide
RT   sequence, open reading frames, and cytochrome P-450 homology of the
RT   Anabaena sp. strain PCC 7120 nifD element.";
RL   J. Bacteriol. 172:6981-6990(1990).
RN   [2]
RP   SEQUENCE REVISION.
RA   Lammers P.J., Trujillo-Provencio C., Sanchez C., Carillo M.;
RL   Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Probably involved in alkane/fatty acid hydroxylase.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U38537; AAC82967.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB73407.1; -; Genomic_DNA.
DR   PIR; AG1987; AG1987.
DR   PIR; C37842; C37842.
DR   RefSeq; WP_010995622.1; NZ_RSCN01000040.1.
DR   AlphaFoldDB; P29980; -.
DR   SMR; P29980; -.
DR   STRING; 103690.17130797; -.
DR   PRIDE; P29980; -.
DR   EnsemblBacteria; BAB73407; BAB73407; BAB73407.
DR   KEGG; ana:alr1450; -.
DR   eggNOG; COG2124; Bacteria.
DR   OMA; GDEHRQM; -.
DR   OrthoDB; 520970at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Monooxygenase; Nitrogen fixation;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..459
FT                   /note="Probable cytochrome P450 110"
FT                   /id="PRO_0000052224"
FT   BINDING         393
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        396
FT                   /note="Y -> I (in Ref. 1; AAC82967)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   459 AA;  52576 MW;  7CC63213C94C5688 CRC64;
     MLTQLPNPIS VPSWWQLINW IADPIGFQKK YSKKYGNIFS MQLAGIGSFV ILGEPQALQE
     IFTQDSRFDV GRGNTLAEPL IGRTSLMLMD GDRHRRERKL LMPPFHGERL QAYAQQICLI
     TNQIASEWQI GQPFVARSAM QKLSLEVIIQ IVFGLADGER YQQIKPLFTD WLNMTDSPLR
     SSMLFLKSLQ KDWGTWTPWG QMKHKQRSIY DLLQAEIEEK RTKENEQRGD VLSLMMAARD
     ENGQAMTDEE LKDELLTILF AGHETTATTI AWAFYQILKN VNVQEKLQQE LDRLGANPNP
     MEIAQLPYLT AVSQETLRMY PVLPTLFPRI TKSSINIAGY QLEPDTTLMA SIYLIHYRED
     LYPNPQQFRP ERFIERQYSP SEYIPFGGGS RRCLGYALAL LEIKLVIATV LSNYQLALAE
     DKPVNVQRRG FTLAPDGGVR VIMTGKKSLK FEQSSKIFN