ID   CPXR_SINFN              Reviewed;         467 AA.
AC   P55543;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Cytochrome P450 BJ-3 homolog;
DE            EC=1.14.14.-;
GN   OrderedLocusNames=NGR_a02710; ORFNames=y4lC;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases.
CC       They oxidize a variety of structurally unrelated compounds, including
CC       steroids, fatty acids, and xenobiotics.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91756.1; -; Genomic_DNA.
DR   PIR; T10879; T10879.
DR   RefSeq; NP_443954.1; NC_000914.2.
DR   RefSeq; WP_010875296.1; NC_000914.2.
DR   AlphaFoldDB; P55543; -.
DR   SMR; P55543; -.
DR   STRING; 394.NGR_a02710; -.
DR   EnsemblBacteria; AAB91756; AAB91756; NGR_a02710.
DR   KEGG; rhi:NGR_a02710; -.
DR   PATRIC; fig|394.7.peg.289; -.
DR   eggNOG; COG2124; Bacteria.
DR   HOGENOM; CLU_033716_1_0_5; -.
DR   OMA; CDFARDV; -.
DR   OrthoDB; 816674at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002397; Cyt_P450_B.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00359; BP450.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..467
FT                   /note="Cytochrome P450 BJ-3 homolog"
FT                   /id="PRO_0000052309"
FT   REGION          444..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        449..467
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         376
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   467 AA;  50695 MW;  42BC64A0E939490D CRC64;
     MDMQETTTAC ADAFAELASP ACIDDPYPFM RWLREHDPVH RAASGLFLLS RHADICWALK
     ATGDAFRGPA PGELARYFPR AATSLSLNLL ASTLAMKEPP THTRLRRLIS RDFTMREIDN
     LRPSIARFVA ARLDGMAPAL ERGEAVDLHR QFALALPMLV FAELFGMPQD DMFGLAAGIG
     AILEGLSPHA SDPQLAAADA ASARMKAYFG DLIQRKCIDP RHDIVATLVG AHDDDADTLS
     DAELISMLWG MLLGGFATTA ATIDHAVLAM LAYPDQRHWL QGDAAGVEAF VEEVLRCDAP
     AMFSSIPRIA QSDIELSGVV IPKNADVRVL IAAGNRDPDA FADPDRFDPA RFYGTSPGMS
     TDGKIMLSFG HGIHFCLGAQ LARVQLAESL PRIQARFPTL TVAEQPTREP SAFLRTFRAL
     PVRLHAQGDS PRLTSAFLNG QRGVEGGASF EHGDGERRSA TDRRAQP