ID   CQ058_MOUSE             Reviewed;         305 AA.
AC   Q08AU9; A0A1B0GR98;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-FEB-2022, sequence version 2.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=UPF0450 protein C17orf58 homolog;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 179-305.
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the UPF0450 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI24998.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAI25007.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; GL456158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC124997; AAI24998.1; ALT_INIT; mRNA.
DR   EMBL; BC125006; AAI25007.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001156945.1; NM_001163473.1.
DR   RefSeq; XP_017170225.1; XM_017314736.1.
DR   AlphaFoldDB; Q08AU9; -.
DR   PhosphoSitePlus; Q08AU9; -.
DR   MaxQB; Q08AU9; -.
DR   PRIDE; Q08AU9; -.
DR   ProteomicsDB; 307750; -.
DR   Antibodypedia; 31734; 66 antibodies from 13 providers.
DR   Ensembl; ENSMUST00000140447; ENSMUSP00000147434; ENSMUSG00000078607.
DR   GeneID; 69066; -.
DR   KEGG; mmu:69066; -.
DR   UCSC; uc007mab.2; mouse.
DR   MGI; MGI:1916316; 1810010H24Rik.
DR   VEuPathDB; HostDB:ENSMUSG00000078607; -.
DR   GeneTree; ENSGT00390000002361; -.
DR   InParanoid; Q08AU9; -.
DR   OrthoDB; 1248778at2759; -.
DR   PhylomeDB; Q08AU9; -.
DR   BioGRID-ORCS; 69066; 2 hits in 17 CRISPR screens.
DR   PRO; PR:Q08AU9; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q08AU9; protein.
DR   Bgee; ENSMUSG00000078607; Expressed in right lung lobe and 108 other tissues.
DR   Gene3D; 2.40.50.120; -; 1.
DR   InterPro; IPR001134; Netrin_domain.
DR   InterPro; IPR008993; TIMP-like_OB-fold.
DR   SUPFAM; SSF50242; SSF50242; 1.
DR   PROSITE; PS50189; NTR; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..305
FT                   /note="UPF0450 protein C17orf58 homolog"
FT                   /id="PRO_0000279446"
FT   DOMAIN          159..304
FT                   /note="NTR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00295"
FT   REGION          18..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        159..233
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00295"
FT   DISULFID        163..237
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00295"
FT   DISULFID        174..304
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00295"
SQ   SEQUENCE   305 AA;  33674 MW;  FAE504D1E7D166B8 CRC64;
     MTARALWLLC LIVGWSPEAP VAERKAPPPH RKPDSRETPG PRAQPLPEFS RRPRAAYAGP
     RAWPDPRRRK TAPPADNRAG FRDAVHAPAA LPGPRLAQAE NRASPPEDSP RRALSRAVRP
     PGARAASPAH PNRPRAAAQP SGTPQALSPE DREPETQSCA RACSADADEW EAYCASEFAV
     NGIVHDVDVL GAGMRLVTLL VDPDGLYKMS RLYITPDGFF FRVHILALDS SSCHKPCPEF
     KPGSRYIVMG HIYHKRRQLP SALLQVLRGR LRPGDGLIRG SSSYVKRFNR KREWQVRGAT
     HTQCI