ID   CQ064_HUMAN             Reviewed;         236 AA.
AC   Q86WR6; Q8IY87;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 2.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized protein C17orf64;
GN   Name=C17orf64;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH36356.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAH48806.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC037475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC036356; AAH36356.1; ALT_INIT; mRNA.
DR   EMBL; BC048806; AAH48806.1; ALT_INIT; mRNA.
DR   CCDS; CCDS32698.2; -.
DR   RefSeq; NP_859058.2; NM_181707.2.
DR   AlphaFoldDB; Q86WR6; -.
DR   SMR; Q86WR6; -.
DR   BioGRID; 125886; 4.
DR   STRING; 9606.ENSP00000269127; -.
DR   iPTMnet; Q86WR6; -.
DR   PhosphoSitePlus; Q86WR6; -.
DR   BioMuta; C17orf64; -.
DR   jPOST; Q86WR6; -.
DR   MassIVE; Q86WR6; -.
DR   PaxDb; Q86WR6; -.
DR   PeptideAtlas; Q86WR6; -.
DR   PRIDE; Q86WR6; -.
DR   ProteomicsDB; 70192; -.
DR   Antibodypedia; 45592; 91 antibodies from 16 providers.
DR   DNASU; 124773; -.
DR   Ensembl; ENST00000269127.5; ENSP00000269127.4; ENSG00000141371.13.
DR   GeneID; 124773; -.
DR   KEGG; hsa:124773; -.
DR   MANE-Select; ENST00000269127.5; ENSP00000269127.4; NM_181707.3; NP_859058.2.
DR   UCSC; uc002iyq.4; human.
DR   CTD; 124773; -.
DR   GeneCards; C17orf64; -.
DR   HGNC; HGNC:26990; C17orf64.
DR   HPA; ENSG00000141371; Tissue enriched (testis).
DR   neXtProt; NX_Q86WR6; -.
DR   OpenTargets; ENSG00000141371; -.
DR   PharmGKB; PA142672247; -.
DR   VEuPathDB; HostDB:ENSG00000141371; -.
DR   eggNOG; KOG0384; Eukaryota.
DR   GeneTree; ENSGT00390000003769; -.
DR   HOGENOM; CLU_095548_0_0_1; -.
DR   InParanoid; Q86WR6; -.
DR   OMA; VPCLETS; -.
DR   OrthoDB; 1232482at2759; -.
DR   PhylomeDB; Q86WR6; -.
DR   TreeFam; TF335849; -.
DR   PathwayCommons; Q86WR6; -.
DR   BioGRID-ORCS; 124773; 7 hits in 1041 CRISPR screens.
DR   GenomeRNAi; 124773; -.
DR   Pharos; Q86WR6; Tdark.
DR   PRO; PR:Q86WR6; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; Q86WR6; protein.
DR   Bgee; ENSG00000141371; Expressed in left testis and 107 other tissues.
DR   ExpressionAtlas; Q86WR6; baseline and differential.
DR   Genevisible; Q86WR6; HS.
DR   InterPro; IPR039880; C17orf64-like.
DR   InterPro; IPR025260; DUF4208.
DR   PANTHER; PTHR21765; PTHR21765; 1.
DR   Pfam; PF13907; DUF4208; 1.
DR   SMART; SM01176; DUF4208; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..236
FT                   /note="Uncharacterized protein C17orf64"
FT                   /id="PRO_0000287174"
FT   REGION          184..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..199
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..216
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   236 AA;  27182 MW;  6C528E415783DDAC CRC64;
     MEASDGQGGE GDKPLEQVTN VSCLETSSSA SPARDSLMRH AKGLDQDTFK TCKEYLRPLK
     KFLRKLHLPR DLPQKKKLKY MKQSLVVLGD HINTFLQHYC QAWEIKHWRK MLWRFISLFS
     ELEAKQLRRL YKYTKSSQPA KFLVTFCASD APERSLLADR EDSLPKLCHA WGLHSNISGM
     KERLSNMQTP GQGSPLPGQP RSQDHVKKDS LRELSQKPKL KRKRIKEAPE TPETEP