CQ077_HUMAN
ID CQ077_HUMAN Reviewed; 243 AA.
AC Q96MU5;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 2.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Uncharacterized protein CD300LD-AS1 {ECO:0000312|HGNC:HGNC:26480};
DE AltName: Full=CD300LD antisense RNA 1;
DE Flags: Precursor;
GN Name=CD300LD-AS1 {ECO:0000312|HGNC:HGNC:26480}; Synonyms=C17orf77;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT SER-47.
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK056444; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AK056444; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AC079325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001289738.1; NM_001302809.1.
DR RefSeq; NP_689673.2; NM_152460.2.
DR AlphaFoldDB; Q96MU5; -.
DR BioGRID; 127006; 2.
DR STRING; 9606.ENSP00000329353; -.
DR GlyGen; Q96MU5; 1 site.
DR iPTMnet; Q96MU5; -.
DR PhosphoSitePlus; Q96MU5; -.
DR BioMuta; HGNC:26480; -.
DR DMDM; 313104095; -.
DR PaxDb; Q96MU5; -.
DR PRIDE; Q96MU5; -.
DR ProteomicsDB; 77410; -.
DR DNASU; 146723; -.
DR GeneID; 146723; -.
DR CTD; 146723; -.
DR GeneCards; CD300LD-AS1; -.
DR HGNC; HGNC:26480; CD300LD-AS1.
DR neXtProt; NX_Q96MU5; -.
DR eggNOG; ENOG502TFID; Eukaryota.
DR InParanoid; Q96MU5; -.
DR OrthoDB; 1112201at2759; -.
DR PhylomeDB; Q96MU5; -.
DR TreeFam; TF342090; -.
DR PathwayCommons; Q96MU5; -.
DR SignaLink; Q96MU5; -.
DR BioGRID-ORCS; 146723; 11 hits in 1043 CRISPR screens.
DR ChiTaRS; C17orf77; human.
DR GenomeRNAi; 146723; -.
DR Pharos; Q96MU5; Tdark.
DR PRO; PR:Q96MU5; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q96MU5; protein.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..243
FT /note="Uncharacterized protein CD300LD-AS1"
FT /id="PRO_0000264239"
FT CARBOHYD 136
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VARIANT 47
FT /note="R -> S (in dbSNP:rs493430)"
FT /evidence="ECO:0000269|PubMed:14702039"
FT /id="VAR_029628"
FT CONFLICT 57
FT /note="S -> T (in Ref. 1; AK056444)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 243 AA; 26264 MW; 43BBBF3D55CDF05A CRC64;
MDELALSFSL TCLLPENRAS LSPSQPLSFQ CLKAPATLTW EDEKQQRWGQ PHGPVSSPLL
GDHRCLVPFR DLNPSSEVNT ANLLESPSSL LLTSCYICSY FSFYILGEKR CHSLKRLRYS
VCCKVCPNFC ACGKENVSGT GQVCTGVHVG AKEQEEPGGT QALRSCGIYC LEERTDKASH
EECRERSTLG RPQCTGLTPS LAGESPCPRL LPGSPTVRHL IASSCPGLSD PLPLPPGTLP
LGS
