ID   CQ078_MOUSE             Reviewed;         290 AA.
AC   Q5QR91; B0QZI9; B9EK11; Q5SWU4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Uncharacterized protein C17orf78 homolog;
GN   Name=Gm11437;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=SWR/J; TISSUE=Liver;
RA   Barber M.C., Travers M.T.;
RT   "Tissue-specific expression of a protein encoding gene located within
RT   intron 1 of the mammalian Acetyl-CoA carboxylase-alpha gene.";
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AJ844653; CAH59902.1; -; mRNA.
DR   EMBL; AL596447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC147775; AAI47776.1; -; mRNA.
DR   EMBL; BC147791; AAI47792.1; -; mRNA.
DR   CCDS; CCDS25184.1; -.
DR   RefSeq; NP_001033021.2; NM_001037932.2.
DR   AlphaFoldDB; Q5QR91; -.
DR   SMR; Q5QR91; -.
DR   STRING; 10090.ENSMUSP00000056084; -.
DR   iPTMnet; Q5QR91; -.
DR   PhosphoSitePlus; Q5QR91; -.
DR   MaxQB; Q5QR91; -.
DR   PaxDb; Q5QR91; -.
DR   PRIDE; Q5QR91; -.
DR   ProteomicsDB; 284009; -.
DR   Antibodypedia; 73298; 83 antibodies from 17 providers.
DR   Ensembl; ENSMUST00000050771; ENSMUSP00000056084; ENSMUSG00000051452.
DR   GeneID; 628813; -.
DR   KEGG; mmu:628813; -.
DR   UCSC; uc007kqi.2; mouse.
DR   MGI; MGI:3650287; Gm11437.
DR   VEuPathDB; HostDB:ENSMUSG00000051452; -.
DR   eggNOG; ENOG502SUFK; Eukaryota.
DR   GeneTree; ENSGT00390000008122; -.
DR   HOGENOM; CLU_083643_0_0_1; -.
DR   InParanoid; Q5QR91; -.
DR   OMA; FIIFEVP; -.
DR   PhylomeDB; Q5QR91; -.
DR   TreeFam; TF337703; -.
DR   BioGRID-ORCS; 628813; 1 hit in 63 CRISPR screens.
DR   ChiTaRS; Gm11437; mouse.
DR   PRO; PR:Q5QR91; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q5QR91; protein.
DR   Bgee; ENSMUSG00000051452; Expressed in jejunum and 6 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031668; DUF4711.
DR   PANTHER; PTHR36870; PTHR36870; 1.
DR   Pfam; PF15829; DUF4711; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..290
FT                   /note="Uncharacterized protein C17orf78 homolog"
FT                   /id="PRO_0000300631"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          153..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          246..276
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..276
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        64
FT                   /note="Q -> R (in Ref. 1; CAH59902)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   290 AA;  32583 MW;  05D252420B2CB6EF CRC64;
     MDTILVFSLM IASYDSNKND LRKSSCQVEQ WPSFFSEDVR SNKDLVVRVP LEIHTDTKGT
     PFIQNQPIAT LRCLGSGRRV TVHLVYSERR PKVKYIMKNL PVITDLPRNS TASPRCHLRA
     TSQFQNGSLL TAFLPGISQC TVYSAKDRSA SSEMVPITTS STTPRSKGDE ATSTGAFPNP
     LTQGIDMSLK RRQKWSLVVK ALIAVTLLLG GAAIIVFVIF EVPCPSQCLR VRQLCQCQWL
     WRRKRKEEDQ KPGTTESQLD SQPEKVKHNV PNSSDSKKTT DIAIIYQTYF