CQ10B_PONAB
ID CQ10B_PONAB Reviewed; 238 AA.
AC Q5RD79;
DT 21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial;
DE Flags: Precursor;
GN Name=COQ10B;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COQ10 family. {ECO:0000305}.
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DR EMBL; CR858037; CAH90278.1; -; mRNA.
DR RefSeq; NP_001125125.1; NM_001131653.1.
DR AlphaFoldDB; Q5RD79; -.
DR SMR; Q5RD79; -.
DR STRING; 9601.ENSPPYP00000014575; -.
DR Ensembl; ENSPPYT00000035459; ENSPPYP00000038416; ENSPPYG00000039065.
DR GeneID; 100172009; -.
DR KEGG; pon:100172009; -.
DR CTD; 80219; -.
DR eggNOG; KOG3177; Eukaryota.
DR GeneTree; ENSGT00940000155367; -.
DR HOGENOM; CLU_079653_0_0_1; -.
DR InParanoid; Q5RD79; -.
DR OrthoDB; 1517528at2759; -.
DR Proteomes; UP000001595; Chromosome 2B.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048039; F:ubiquinone binding; IEA:InterPro.
DR GO; GO:0045333; P:cellular respiration; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901; PTHR12901; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..37
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 38..238
FT /note="Coenzyme Q-binding protein COQ10 homolog B,
FT mitochondrial"
FT /id="PRO_0000228649"
SQ SEQUENCE 238 AA; 27087 MW; B027EB087E5B9B06 CRC64;
MAARTGHTSL RRVVSGCRPK SATAAGAQAP VRNGRYLASC GILMSRTLPL HTSILPKEIC
ARTFFKITAP LINKRKEYSE RRILGYSMQE MYDVVSGVED YKHFVPWCKK SDVISKRSGY
CKTRLEIGFP PVLERYTSVV TLVKPHLVKA SCTDGRLFNH LETIWRFSPG LPGYPRTCTL
DFSISFEFRS LLHSQLATLF FDEVVKQMVA AFERRACKLY GPETNIPREL MLHEVHHT