ID   CQ113_HUMAN             Reviewed;         675 AA.
AC   A0A1B0GUU1;
DT   27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Transmembrane protein C17orf113 {ECO:0000305};
GN   Name=C17orf113 {ECO:0000312|HGNC:HGNC:53437};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
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DR   EMBL; AC105024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS86598.1; -.
DR   RefSeq; XP_003960787.2; XM_003960738.5.
DR   RefSeq; XP_011507066.1; XM_011508764.1.
DR   RefSeq; XP_011507067.1; XM_011508765.2.
DR   RefSeq; XP_011507068.1; XM_011508766.2.
DR   RefSeq; XP_011522777.1; XM_011524475.2.
DR   RefSeq; XP_011522778.1; XM_011524476.1.
DR   RefSeq; XP_011522779.1; XM_011524477.2.
DR   RefSeq; XP_011522780.1; XM_011524478.2.
DR   AlphaFoldDB; A0A1B0GUU1; -.
DR   BioMuta; C17orf113; -.
DR   PeptideAtlas; A0A1B0GUU1; -.
DR   Ensembl; ENST00000587304.3; ENSP00000490245.1; ENSG00000267221.3.
DR   MANE-Select; ENST00000587304.3; ENSP00000490245.1; NM_001358661.2; NP_001345590.1.
DR   GeneCards; C17orf113; -.
DR   HGNC; HGNC:53437; C17orf113.
DR   HPA; ENSG00000267221; Low tissue specificity.
DR   neXtProt; NX_A0A1B0GUU1; -.
DR   VEuPathDB; HostDB:ENSG00000267221; -.
DR   GeneTree; ENSGT00940000154994; -.
DR   OMA; VYWMAKE; -.
DR   BioGRID-ORCS; 201181; 4 hits in 185 CRISPR screens.
DR   GenomeRNAi; 201181; -.
DR   Pharos; A0A1B0GUU1; Tdark.
DR   PRO; PR:A0A1B0GUU1; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; A0A1B0GUU1; protein.
DR   Bgee; ENSG00000267221; Expressed in oviduct epithelium and 112 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..675
FT                   /note="Transmembrane protein C17orf113"
FT                   /id="PRO_0000441414"
FT   TRANSMEM        593..613
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   675 AA;  72432 MW;  0C2C54027A7534B5 CRC64;
     MVPPGKKPAG EASNSNKKCK RYFNEHWKEE FTWLDFDYER KLMFCLECRQ ALVRNKHGKA
     ENAFTVGTDN FQRHALLRHV TSGAHRQALA VNQGQPPFEG QAEGGGACPG LATTPASRGV
     KVELDPAKVA VLTTVYCMAK EDVPNDRCSA LLELQRFNLC QALLGTEHGD YYSPRRVRDM
     QVAIASVLHT EACQRLKASP YVGLVLDETR DWPESHSLAL FATSVSPCDG QPATTFLGSV
     ELQEGEATAG QLLDILQAFG VSAPKLAWLS SSLPSERLGS VGPQLRATCP LLAELHCLPG
     RTDPEPPAYL GQYESILDAL FRLHGGPSSH LVPELRAALD LAAIDLAGPR PVPWASLLPV
     VEAVAEAWPG LVPTLEAAAL ASPVAGSLAL ALRQFTFVAF THLLLDALPS VQKLSLVLQA
     EEPDLALLQP LVMAAAASLQ AQRGSGGARL QGFLQELASM DPDASSGRCT YRGVELLGYS
     EAAVRGLEWL RGSFLDSMRK GLQDSYPGPS LDAVAAFAAI FDPRRYPQAP EELGTHGEGA
     LRVLLRGFAP AVVRQRALGD FALFKRVVFG LGRLGPRALC TQLACAHSEL HELFPDFAAL
     AALALALPAG AGLLDKVGRS RELRWWGQSG AGEGRGGHMV KIAVDGPPLH EFDFGLAVEF
     LESGWGEGFL GSQLT